Cross‐talk between clinical and host‐response parameters of periodontitis in smokers

R Nagarajan, CS Miller, D Dawson III… - Journal of …, 2017 - Wiley Online Library
Background and Objective Periodontal diseases are a major public health concern leading
to tooth loss and have also been shown to be associated with several chronic systemic …

Comparative transcriptome analysis of gingival immune-mediated inflammation in peri-implantitis and periodontitis within the same host environment

S Yuan, C Wang, W Jiang, Y Wei, Q Li… - Journal of …, 2022 - Taylor & Francis
Objective This investigation aimed to determine whether and to what extent there are
transcriptional differences between periodontitis and peri-implantitis in the same susceptible …

Dysbiosis and alterations in predicted functions of the subgingival microbiome in chronic periodontitis

ME Kirst, EC Li, B Alfant, YY Chi, C Walker… - Applied and …, 2015 - Am Soc Microbiol
Chronic periodontitis is an inflammatory disease of the periodontium affecting nearly 65
million adults in the United States. Changes in subgingival microbiota have long been …

Immunological link between periodontitis and type 2 diabetes deciphered by single‐cell RNA analysis

H Lee, JY Joo, JM Song, HJ Kim… - Clinical and …, 2023 - Wiley Online Library
Background Type 2 diabetes mellitus (DM) is a complex metabolic disorder that causes
various complications, including periodontitis (PD). Although a bidirectional relationship has …

Transcriptomic analysis reveals the potential crosstalk genes and immune relationship between IgA nephropathy and periodontitis

X Gao, Z Guo, P Wang, Z Liu, Z Wang - Frontiers in Immunology, 2023 - frontiersin.org
Background It is well known that periodontitis has an important impact on systemic diseases.
The aim of this study was to investigate potential crosstalk genes, pathways and immune …

Structure and function of oral microbial community in periodontitis based on integrated data

Z Cai, S Lin, S Hu, L Zhao - Frontiers in cellular and infection …, 2021 - frontiersin.org
Objective Microorganisms play a key role in the initiation and progression of periodontal
disease. Research studies have focused on seeking specific microorganisms for diagnosing …

Bioinformatics reveals the pathophysiological relationship between diabetic nephropathy and periodontitis in the context of aging

P Yan, B Ke, X Fang - Heliyon, 2024 - cell.com
Diabetic nephropathy (DN) is one of the most common microvascular complications of
diabetes mellitus. Periodontitis (PD) is a microbially-induced chronic inflammatory disease …

Discrimination of bacterial community structures among healthy, gingivitis, and periodontitis statuses through integrated metatranscriptomic and network analyses

T Nemoto, T Shiba, K Komatsu, T Watanabe… - Msystems, 2021 - Am Soc Microbiol
Periodontal disease is an inflammatory condition caused by polymicrobial infection. The
inflammation is initiated at the gingiva (gingivitis) and then extends to the alveolar bone …

Integrated analysis and exploration of potential shared gene signatures between carotid atherosclerosis and periodontitis

Y Zeng, S Cao, M Chen - BMC Medical Genomics, 2022 - Springer
Background Increasing evidence has suggested an association between carotid
atherosclerosis (CAS) and periodontitis (PD); however, the mechanisms have not been fully …

Epigenetic characteristics in inflammatory candidate genes in aggressive periodontitis

S Schulz, UD Immel, L Just, HG Schaller, C Gläser… - Human immunology, 2016 - Elsevier
Background Periodontitis is a chronic inflammatory disease triggered by the host immune
response. Epigenetic modifications also affect the immune response. We assessed CpG …