Chronic kidney disease (CKD) has diverse phenotypic manifestations including structural
(such as fibrosis) and functional (such as glomerular filtration rate and albuminuria) …

Gene expression fingerprints in human tubulointerstitial inflammation and fibrosis as
prognostic markers of disease progression. Background Gene expression profiling of …

Current classification of chronic kidney disease (CKD) into stages using indirect systemic
measures (estimated glomerular filtration rate (eGFR) and albuminuria) is agnostic to the …

Abstract Background/Aims: Chronic kidney disease (CKD) is a worldwide public health
problem. Regardless of the underlying primary disease, CKD tends to progress to end-stage …

Although chronic kidney disease (CKD) is common, only a fraction of CKD patients progress
to end-stage renal disease. Molecular predictors to stratify CKD populations according to …

Introduction To develop effective therapies and identify novel early biomarkers for chronic
kidney disease, an understanding of the molecular mechanisms orchestrating it is essential …

Background Diabetic nephropathy (DN) is the most common cause of end-stage renal
disease, affecting∼ 30% of the rapidly growing diabetic population, and strongly associated …

Chronic kidney disease (CKD) affects 8 to 16% people worldwide, with an increasing
incidence and prevalence of end-stage kidney disease (ESKD). The effective management …

OBJECTIVE Diabetic kidney disease (DKD) is the single leading cause of kidney failure in
the US, for which a cure has not yet been found. The aim of our study was to provide an …

In chronic kidney disease (CKD), progressive nephron loss causes glomerular sclerosis, as
well as tubulointerstitial fibrosis and progressive tubular injury. In this study, we aimed to …