G-protein-coupled receptors (GPCRs) are physiologically important membrane proteins that
sense signalling molecules such as hormones and neurotransmitters, and are the targets of …

G-protein-coupled receptors (GPCRs) mediate most of our physiological responses to
hormones, neurotransmitters and environmental stimulants, and so have great potential as …

G protein–coupled receptors (GPCRs) are versatile molecular machines that regulate the
majority of physiological responses to chemically diverse hormones and neurotransmitters …

G protein-coupled receptors (GPCRs) are critical regulators of human physiology and make
up the largest single class of therapeutic drug targets. Although GPCRs regulate highly …

G-protein-coupled receptors (GPCRs) are key cell-surface proteins that transduce external
environmental cues into biochemical signals across the membrane. GPCRs are intrinsically …

G protein-coupled receptors (GPCRs) are targeted by∼ 30–40% of marketed drugs, and
their key roles in normal physiology and in disease demonstrate that an understanding of …

G protein-coupled receptors (GPCRs), the largest family of human membrane proteins and
an important class of drug targets, play a role in maintaining numerous physiological …

The G protein-coupled receptor (GPCR) superfamily constitutes the largest collection of cell
surface signaling proteins with approximately 800 members in the human genome. GPCRs …

G protein-coupled receptors (GPCRs) are a key drug target class. They account for over one-
third of current pharmaceuticals, and both drugs that inhibit and promote receptor function …

G protein-coupled receptors (GPCRs) are privileged structural scaffolds in biology that have
the versatility to regulate diverse physiological processes. Interestingly, many GPCR ligands …