RNA interference (RNAi) is a complex process that uses small RNAs of 21–23 nucleotides to
guide sequence-specific silencing of genetic information at both the transcriptional and …

RNA interference (RNAi) is the sequence-specific gene silencing induced by double-
stranded RNA. RNAi is mediated by 21-23 nucleotide small interfering RNAs (siRNAs) …

microRNAs (miRNAs) are a large family of 21-to 22-nucleotide non-coding RNAs that
interact with target mRNAs at specific sites to induce cleavage of the message or inhibit …

RNase III Dicer produces small RNAs guiding sequence‐specific regulations, with important
biological roles in eukaryotes. Major Dicer‐dependent mechanisms are RNA interference …

Canonical RNA interference (RNAi) is sequence-specific mRNA degradation guided by
small interfering RNAs (siRNAs) made by RNase III Dicer from long double-stranded RNA …

With the discovery of RNA interference (RNAi) and related phenomena, new regulatory roles
attributed to RNA continue to emerge. Here we show, in mammalian tissue culture, that a …

Summary Drosophila Dicer-1 produces microRNAs (miRNAs) from pre-miRNA, whereas
Dicer-2 generates small interfering RNAs (siRNAs) from long dsRNA. Alternative splicing of …

With the explosion of genomic information, there is an increasing need to analyze gene
function in a high-throughput fashion. This makes reverse genetic approaches extremely …

RNA interference is a highly evolutionarily conserved cellular mechanism of gene regulation
in which the own sequences of a gene turn it off. Also, the exogenous double-stranded RNA …

Drosophila melanogaster has two Dicer proteins with specialized functions. Dicer-1 liberates
miRNA-miRNA* duplexes from precursor miRNAs (pre-miRNAs), whereas Dicer-2 …