The concept that inflammation governs atherosclerosis and its complications has provided a
new unifying hypothesis of the links between risk factors and the cellular and molecular …

Many experimental data have suggested that the renin-angiotensin system participates in
immune and inflammatory responses. Angiotensin II is involved in several steps of the …

Until recently, most envisaged atherosclerosis as a bland arterial collection of cholesterol,
complicated by smooth muscle cell accumulation. According to that concept, endothelial …

Inflammation, Atherosclerosis, and Coronary Artery Disease | New England Journal of Medicine
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Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

Inflammation, oxidative stress and hypertension are closely interrelated. Here we discuss
the (patho) physiology of vascular inflammation in hypertension, focusing specifically on the …

Atherogenesis has been traditionally viewed as a metabolic disease representing arterial
obstruction by fatty deposits in its wall. Today, it is believed that atherogenesis involves …

Reactive oxygen species, particularly superoxide, promote endothelial dysfunction and
alterations in vascular structure. It is increasingly recognized that inflammatory cytokines …

Atherosclerosis is the leading cause of vascular disease worldwide and contributes
significantly to deaths from cardiovascular complications. There is a remarkably close …