Based on laboratory and experimental evidence, it has been hypothesized that inflammation
plays a fundamental role in atherogenesis and acute thrombosis. From an epidemiologic …

Following Russel Ross [1], there is now general agreement that vessel wall inflammation
constitutes a major factor in the development of atherosclerosis, atheroma instability and …

Inflammatory monocytes and macrophages have been identified as key players in the
pathogenesis of atherosclerosis, arterial hypertension, and myocardial infarction (MI). They …

Atherosclerosis is a disease of arteries and is characterized by endothelial dysfunction,
vascular inflammation, and the build-up of lipids, cholesterol, calcium, and cellular debris …

Background—Cardiovascular ischemic events may occur more frequently in hypertensive
patients with activated renin-angiotensin systems. We tested the hypothesis that angiotensin …

Diseases such as hypertension, atherosclerosis, hyperlipidemia, and diabetes are
associated with vascular functional and structural changes including endothelial …

Inflammation drives coronary artery disease and atherosclerosis implications. Lipoprotein
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …

The RAAS through its physiological effectors plays a key role in promoting and maintaining
inflammation. Inflammation is an important mechanism in the development and progression …

Vascular injury, characterized by endothelial dysfunction, structural remodelling,
inflammation and fibrosis, plays an important role in cardiovascular diseases. Cellular …

Background Among the markers of inflammation, a cytokine, interleukin (IL)-6, promotes the
expression of intercellular adhesion molecule 1 (ICAM-1), C-reactive protein (CRP) …