Parkinson's disease (PD) is the most common movement disorder. The neuropathology is
characterized by the loss of dopamine neurons in the substantia nigra pars compacta …

Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease and it is characterized by the progressive loss of dopaminergic neurons …

Current findings suggest that multipotent stem cells may be suitable for cell replacement
therapies in the treatment of neurodegenerative disorders. Embryonic stem (ES) cells are …

Background: Cell transplantation to replace lost neurons in neurodegenerative diseases
such as Parkinson's disease (PD) offers a hopeful prospect for many patients. Previously …

Parkinson's disease (PD) manifests with a typical movement disorder, due to the loss of
dopaminergic neurons of the substantia nigra. There are no disease-modifying treatments …

Motor dysfunctions in Parkinson's disease are considered to be primarily due to the
degeneration of dopaminergic neurons in the substantia nigra pars compacta …

Parkinson's disease is one of the most common neurodegenerative diseases caused by the
loss of dopaminergic neurons in the substantia nigra pars compacta. Pharmacological …

Clinical studies with intrastriatal transplants of human embryonic mesencephalic tissue have
provided proof-of-principle for the cell replacement strategy in Parkinson's disease (PD) …

Early clinical trials designed to treat Parkinson's disease by transplantation of fetal tissue
containing dopamine neuron precursors yielded promising results, but the approach retains …

A major neuropathological feature of Parkinson's disease (PD) is the loss of nigrostriatal
dopaminergic neuron. Patients exhibit motor symptoms, including bradykinesia, rigidity, and …