Good cholesterol gone bad? HDL and COVID-19

GEG Kluck, JA Yoo, EH Sakarya, BL Trigatti - International journal of …, 2021 - mdpi.com
The transmissible respiratory disease COVID-19, caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has affected millions of people worldwide since its …

SARS‐CoV‐2 induced HDL dysfunction may affect the host's response to and recovery from COVID‐19

HM Al‐kuraishy, NR Hussien… - Immunity …, 2023 - Wiley Online Library
Introduction Covid‐19 is linked with the development of cardio‐metabolic disorders,
including dyslipidemia, dysregulation of high‐density lipoprotein (HDL), and low‐density …

The role of high-density lipoprotein in COVID-19

G Wang, J Deng, J Li, C Wu, H Dong, S Wu… - Frontiers in …, 2021 - frontiersin.org
The current Coronavirus disease 2019 (COVID-19) pandemic has become a global
challenge. Managing a large number of acutely ill patients in a short time, whilst reducing …

[HTML][HTML] High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner

Y Correa, R Del Giudice, S Waldie, M Thépaut… - Journal of Colloid and …, 2023 - Elsevier
There is a close relationship between the SARS-CoV-2 virus and lipoproteins, in particular
high-density lipoprotein (HDL). The severity of the coronavirus disease 2019 (COVID-19) is …

Cholesterol Metabolism—Impacts on SARS-CoV-2 Infection Prognosis, Entry, and Antiviral Therapies

C Wei, L Wan, Y Zhang, C Fan, Q Yan, X Yang, J Gong… - MedRxiv, 2020 - medrxiv.org
The recently emerged pathogenic SARS-coronavirus 2 (SARS-CoV-2) has spread rapidly,
leading to a global pandemic. In this study, we show that SARS-CoV-2 infection was …

Low HDL cholesterol efflux capacity indicates a fatal course of COVID-19

JT Stadler, H Mangge, A Rani, P Curcic, M Herrmann… - Antioxidants, 2022 - mdpi.com
Plasma membrane cholesterol is required for proper trafficking and localization of receptors
that facilitate severe acute respiratory syndrome coronavirus 2 infection. High-density …

HDL-related parameters and COVID-19 mortality: the importance of HDL function

JT Stadler, H Habisch, F Prüller, H Mangge… - Antioxidants, 2023 - mdpi.com
COVID-19, caused by the SARS-CoV-2 coronavirus, emerged as a global pandemic in late
2019, resulting in significant global public health challenges. The emerging evidence …

Multifaced roles of HDL in sepsis and SARS-CoV-2 infection: Renal implications

A Stasi, R Franzin, M Fiorentino… - International journal of …, 2021 - mdpi.com
High-density lipoproteins (HDLs) are a class of blood particles, principally involved in
mediating reverse cholesterol transport from peripheral tissue to liver. Omics approaches …

HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry

C Wei, L Wan, Q Yan, X Wang, J Zhang, X Yang… - Nature …, 2020 - nature.com
Responsible for the ongoing coronavirus disease 19 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through binding of the …

Altered high-density lipoprotein composition and functions during severe COVID-19

F Begue, S Tanaka, Z Mouktadi, P Rondeau… - Scientific reports, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) pandemic is affecting millions of patients
worldwide. The consequences of initial exposure to SARS-CoV-2 go beyond pulmonary …