A novel nano therapeutic using convalescent plasma derived exosomal (CPExo) for COVID-19: A combined hyperactive immune modulation and diagnostics

K Anand, C Vadivalagan, JS Joseph, SK Singh… - Chemico-Biological …, 2021 - Elsevier
Extracellular vesicles like exosomes are important therapeutic tactics for treating COVID-19.
By utilizing convalescent plasma derived exosomes (CP Exo) from COVID-19 recovered …

Exosomes derived from bone marrow mesenchymal stem cells as treatment for severe COVID-19

V Sengupta, S Sengupta, A Lazo, P Woods… - Stem cells and …, 2020 - liebertpub.com
This prospective nonrandomized open-label cohort study addresses the safety and efficacy
of exosomes (ExoFlo™) derived from allogeneic bone marrow mesenchymal stem cells as …

Hypothesis for the management and treatment of the COVID-19-induced acute respiratory distress syndrome and lung injury using mesenchymal stem cell-derived …

M Taghavi-Farahabadi, M Mahmoudi, S Soudi… - Medical hypotheses, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a member of the
coronaviridae that causes respiratory disorders. After infection, large amounts of …

Nebulized exosomes derived from allogenic adipose tissue mesenchymal stromal cells in patients with severe COVID-19: a pilot study

YG Zhu, M Shi, A Monsel, C Dai, X Dong… - Stem cell research & …, 2022 - Springer
Background Existing clinical studies supported the potential efficacy of mesenchymal
stromal cells as well as derived exosomes in the treatment of COVID-19. We aimed to …

The role of extracellular vesicles in COVID-19 virus infection

M Hassanpour, J Rezaie, M Nouri, Y Panahi - Infection, Genetics and …, 2020 - Elsevier
Extracellular vesicles releasing from various types of cells contribute to intercellular
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …

Extracellular vesicle-based therapy for COVID-19: Promises, challenges and future prospects

V Karn, S Ahmed, LW Tsai, R Dubey, S Ojha, HN Singh… - Biomedicines, 2021 - mdpi.com
The COVID-19 pandemic has become a serious concern and has negatively impacted
public health and the economy. It primarily targets the lungs, causing acute respiratory …

Mesenchymal stem cell derived extracellular vesicles: promising immunomodulators against autoimmune, autoinflammatory disorders and SARS-CoV-2 infection

O Bulut, İ Gürsel - Turkish Journal of Biology, 2020 - journals.tubitak.gov.tr
Discovery of novel and broad-acting immunomodulators is of critical importance for the
prevention and treatment of disorders occurring due to overexuberant immune …

The immunomodulatory role of cell-free approaches in SARS-coV-2-induced cytokine storm—A powerful therapeutic tool for COVID-19 patients

M Csobonyeiova, V Smolinska, S Harsanyi… - Biomedicines, 2023 - mdpi.com
Currently, there is still no effective and definitive cure for the coronavirus disease 2019
(COVID-19) caused by the infection of the novel highly contagious severe acute respiratory …

Preclinical studies on convalescent human immune plasma-derived exosome: Omics and antiviral properties to SARS-CoV-2

NP Taşlı, ZB Gönen, OK Kırbaş, NS Gökdemir… - Frontiers in …, 2022 - frontiersin.org
The scale of the COVID-19 pandemic forced urgent measures for the development of new
therapeutics. One of these strategies is the use of convalescent plasma (CP) as a …

Biogenesis, composition and potential therapeutic applications of mesenchymal stem cells derived exosomes in various diseases

YG Yuan, JL Wang, YX Zhang, L Li… - International Journal …, 2023 - Taylor & Francis
Exosomes are nanovesicles with a wide range of chemical compositions used in many
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …