Bone marrow mesenchymal stem cell-derived extracellular vesicle infusion for the treatment of respiratory failure from COVID-19: a randomized, placebo-controlled …

AL Lightner, V Sengupta, S Qian, JT Ransom, S Suzuki… - Chest, 2023 - Elsevier
Background Bone marrow mesenchymal stem cell (BM-MSC)-derived extracellular vesicles
(ExoFlo) convey the immunomodulatory and regenerative properties of intact BM-MSCs …

Exosomes and COVID-19: challenges and opportunities

G Babaei, N Zare, A Mihanfar, MHK Ansari - Comparative Clinical …, 2022 - Springer
Abstract Coronavirus disease 2019 or COVID-19, starting from Wuhan, China, in December
2019, is a pandemic situation affecting millions worldwide and has exerted a huge burden …

Extracellular vesicles in COVID-19 prognosis, treatment, and vaccination: An update

A Hernández-Díazcouder, C Díaz-Godínez… - Applied Microbiology …, 2023 - Springer
The lethality of the COVID 19 pandemic became the trigger for one of the most meteoric
races on record in the search for strategies of disease control. Those include development of …

Possibility of exosome‑based coronavirus disease 2019 vaccine

KH Yoo, N Thapa, BJ Kim, JO Lee… - Molecular …, 2022 - spandidos-publications.com
Abstract Coronavirus disease 2019 (COVID‑19) is a global pandemic that can have a long‑
lasting impact on public health if not properly managed. Ongoing vaccine development trials …

Allogenic mesenchymal stromal cells and their extracellular vesicles in COVID-19 induced ARDS: a randomized controlled trial

M Zarrabi, MA Shahrbaf, M Nouri, F Shekari… - Stem Cell Research & …, 2023 - Springer
Background and aims The main causes of death in patients with severe Coronavirus
disease-2019 (COVID-19) are acute respiratory distress syndrome (ARDS) and multiorgan …

Meet changes with constancy: Defence, antagonism, recovery, and immunity roles of extracellular vesicles in confronting SARS‐CoV‐2

X Chen, H Li, H Song, J Wang, X Zhang… - Journal of …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), has wrought havoc on the world economy and …

Are mesenchymal stem cells and derived extracellular vesicles valuable to halt the COVID-19 inflammatory cascade? Current evidence and future perspectives

M Monguió-Tortajada, A Bayes-Genis, A Rosell… - Thorax, 2021 - thorax.bmj.com
Clinical management of patients suffering from COVID-19 includes infection prevention,
control measures and supportive care, including supplemental oxygen and mechanical …

Potential therapeutic applications of extracellular vesicles in the immunopathogenesis of COVID-19

M Motallebnezhad, M Omraninava, HEG Ghaleh… - … -Research and Practice, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the cause of
coronavirus disease 2019 (COVID-19) which has emerged as a global health crisis …

[HTML][HTML] Are mesenchymal stem cells able to manage cytokine storm in COVID-19 patients? A review of recent studies

NK Farkhad, H Reihani, AA Moghadam… - Regenerative …, 2021 - Elsevier
The Covid-19 disease has recently become one of the biggest challenges globally, and
there is still no specific medication. Findings showed the immune system in severe Covid-19 …

Therapeutic features and updated clinical trials of mesenchymal stem cell (MSC)-derived exosomes

BC Lee, I Kang, KR Yu - Journal of clinical medicine, 2021 - mdpi.com
Identification of the immunomodulatory and regenerative properties of mesenchymal stem
cells (MSCs) have made them an attractive alternative therapeutic option for diseases with …