Transfusion of plasma can lead to adverse reactions or events. Immune-mediated reactions
are most common—these include allergic and anaphylactic reactions, transfusion-related …

Protein products prepared from pooled human plasma are an essential class of therapeutics
used mostly to control bleeding and/or immunological disorders. Because of the human …

Plasma utilization has increased over the past two decades, and there is a growing concern
that many plasma transfusions are inappropriate. Plasma transfusion is not without risk, and …

A substantial body of animal data indicates that transmissible spongiform encephalopathies
(TSEs) are transmitted through blood. These data have been augmented in the past year by …

The emergence of the variant Creutzfeldt-Jakob disease in the mid 1990s soon raised
concerns about its possible transmission through the use of blood and plasma-derived …

Substantial improvement in the safety of blood transfusion has been achieved through the
addition of new tests, such as nucleic acid tests, yet residual risk associated with transfusion …

There have been four highly probable instances of variant Creutzfeldt‐Jakob disease
(vCJD) transmission by non‐leucocyte depleted red cell concentrates and it is now clear that …

Due to its significant role in saving lives, blood transfusion became one of the most
commonly used therapies in medicine. In the USA red blood cell transfusions, for instance …

Millions of units of blood products are transfused annually to patients in the United States.
Red blood cells are transfused to improve oxygen-carrying capacity in patients with or at …

Both fresh frozen plasma (FFP) and platelets are heavily used in massive transfusion.
Although FFP can partially correct abnormal coagulation, a recent systematic review …