HDL: Quality or quantity?

CG Santos-Gallego - Atherosclerosis, 2015 - atherosclerosis-journal.com
In the last six decades, high density lipoproteins (HDL) have been extensively considered to
reduce the risk for coronary artery disease (CAD); in fact, the cholesterol carried by HDL …

HDL re-examined

GK Hovingh, DJ Rader, RA Hegele - Current opinion in lipidology, 2015 - journals.lww.com
The dogmatic concept that HDL-C levels predict future CVD events is undisputed, but the
role of HDL-C as a causal factor in atherosclerosis has been challenged by a number of …

HDL: to treat or not to treat?

A Pirillo, G Tibolla, GD Norata, AL Catapano - Current atherosclerosis …, 2014 - Springer
Several studies have shown an inverse relationship between HDL cholesterol (HDL-C)
levels and the risk of cardiovascular disease. Low HDL-C levels are commonly present in …

HDL-cholesterol and cardiovascular disease: rethinking our approach

HK Siddiqi, D Kiss, D Rader - Current opinion in cardiology, 2015 - journals.lww.com
HDL-cholesterol and cardiovascular disease: rethinking our a... : Current Opinion in
Cardiology HDL-cholesterol and cardiovascular disease: rethinking our approach : Current …

HDL and cardiovascular disease

DJ Rader, GK Hovingh - The Lancet, 2014 - thelancet.com
The cholesterol contained within HDL is inversely associated with risk of coronary heart
disease and is a key component of predicting cardiovascular risk. However, despite its …

HDL in morbidity and mortality: a 40+ year perspective

AR Tall - Clinical Chemistry, 2021 - academic.oup.com
The first large population-based study to show an inverse relationship between circulating
HDL-cholesterol (HDL-C) concentrations and coronary heart disease (CHD) was a cross …

[PDF][PDF] Dysfunctional HDL: from structure-function-relationships to biomarkers

M Riwanto, L Rohrer, A von Eckardstein… - High Density …, 2015 - library.oapen.org
Reduced plasma levels of HDL-C are associated with an increased risk of CAD and
myocardial infarction, as shown in various prospective population studies. However, recent …

HDL as a Treatment Target: Should We Abandon This Idea?

F Begue, ML Apalama, G Lambert… - Current Atherosclerosis …, 2023 - Springer
Abstract Purpose of Review High-density lipoproteins (HDL) have long been regarded as an
antiatherogenic lipoprotein species by virtue of their role in reverse cholesterol transport …

Is a high HDL-cholesterol level always beneficial?

B Franczyk, J Rysz, J Ławiński, M Rysz-Górzyńska… - Biomedicines, 2021 - mdpi.com
The specific interest concerning HDL cholesterol (HDL-C) is related to its ability to uptake
and return surplus cholesterol from peripheral tissues back to the liver and, therefore, to its …

Therapeutic approaches to raising plasma HDL-cholesterol levels

MM Thompson, SC Reed, GW Cockerill - Nature Clinical Practice …, 2004 - nature.com
Epidemiologic data from the Framingham and Prospective Cardiovascular Munster studies,
demonstrating an inverse correlation between the plasma concentration of HDLs and the …