Cortisol, dehydroepiandrosterone sulfate, fatty acids, and their relation in recurrent depression

DM Ter Horst, AH Schene, CA Figueroa… - …, 2019 - Elsevier
Background Alterations in hypothalamic–pituitary–adrenal (HPA)-axis activity, fatty acid
metabolism, and their relation have been associated with (recurrent) major depressive …

[HTML][HTML] Relationship between the hypothalamic–pituitary–adrenal-axis and fatty acid metabolism in recurrent depression

RJT Mocking, HG Ruhé, J Assies, A Lok… - …, 2013 - Elsevier
Alterations in hypothalamic–pituitary–adrenal (HPA)-axis activity and fatty acid (FA)-
metabolism have been observed in (recurrent) major depressive disorder (MDD). Through …

DHEAS and cortisol/DHEAS-ratio in recurrent depression: state, or trait predicting 10-year recurrence?

RJT Mocking, CM Pellikaan, A Lok, J Assies… - …, 2015 - Elsevier
Background Major depressive disorder (MDD) has been associated with low
dehydroepiandrosterone-sulphate (DHEAS),–particularly relative to high cortisol–although …

Morning salivary dehydroepiandrosterone (DHEA) qualifies as the only neuroendocrine biomarker separating depressed patients with and without prior history of …

A Agorastos, A Heinig, A Sommer… - Journal of Psychiatric …, 2023 - Elsevier
Background Hypothalamic-pituitary-adrenal (HPA) axis abnormalities in major depression
(MDD) have been consistently reported in psychiatry and extend to several neurosteroids …

[HTML][HTML] Longitudinal hypothalamic–pituitary–adrenal axis trait and state effects in recurrent depression

A Lok, RJT Mocking, HG Ruhé, I Visser… - …, 2012 - Elsevier
BACKGROUND: Hypothalamic–pituitary–adrenal (HPA)-axis hyperactivity has been
observed in (recurrent) major depressive disorder (MDD), although inconsistently and …

Fatty acid metabolism and its longitudinal relationship with the hypothalamic–pituitary–adrenal axis in major depression: associations with prospective antidepressant …

RJT Mocking, HF Verburg, AM Westerink… - …, 2015 - Elsevier
Background Metabolism of dietary fatty acids (FAs), and its relationship with the
hypothalamic–pituitary–adrenal (HPA)-axis, have been found to be altered in major …

Combined dexamethasone/CRF test in remitted outpatients with recurrent major depressive disorder

F Van Den Eede, B Van den Bossche, W Hulstijn… - Journal of affective …, 2006 - Elsevier
BACKGROUND: Hyperactivity of the hypothalamic–pituitary–adrenal (HPA) axis is a
prominent neurobiological finding during a major depressive episode, reflecting a state …

Biological profiling of prospective antidepressant response in major depressive disorder: associations with (neuro) inflammation, fatty acid metabolism, and amygdala …

RJT Mocking, TS Nap, AM Westerink, J Assies… - …, 2017 - Elsevier
Background A better understanding of factors underlying antidepressant non-response may
improve the prediction of which patients will respond to what treatment. Major depressive …

HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients

EB Binder, HE Künzel, T Nickel, N Kern… - …, 2009 - Elsevier
A concatenation of data implicates a hyperactivity of the hypothalamus pituitary adrenal
(HPA)-axis in the pathogenesis of depression and its normalization as a necessary …

Elevated salivary dehydroepiandrosterone-sulfate but normal cortisol levels in medicated depressed patients: preliminary findings

J Assies, I Visser, NA Nicolson, TA Eggelte… - Psychiatry …, 2004 - Elsevier
Major depression is often associated with dysregulation of the hypothalamic-pituitary-
adrenal (HPA) axis. In contrast to cortisol, dehydroepiandrosterone-sulfate (DHEA-S) has …