Background: Cognitive impairment is a major problem in elderly, affecting quality of life. Pre-
clinical studies show that MMFS-01, a synapse density enhancer, is effective at reversing …

The rapid aging of populations around the world has become an unprecedented challenge.
Aging is associated with cognitive impairment, including dementia and mild cognitive …

INTRODUCTION This study primarily aimed to evaluate the efficacy and safety of
SaiLuoTong (SLT) on cognition in mild cognitive impairment (MCI). METHODS Community …

Objectives: Improving the sleep of older adults with mild cognitive impairment (MCI)
represents a first step in discovering whether interventions directed at modifying this risk …

Background Effective, disease-modifying therapeutics for the treatment of Alzheimer's
disease (AD) remain a large unmet need. Extensive evidence suggests that amyloid beta …

As neuroinflammation is an early event in the pathogenesis of Alzheimer's disease, new
selective antiinflammatory drugs could lead to promising preventive strategies. We …

(S)-2, 3-dihydro-[3, 4] cyclopentano-1, 2, 4-benzothiadiazine-1, 1-dioxide (S 18986-1) is a
new compound that facilitates post-synaptic responses by modulating α-amino-3-hydroxy-5 …

Abstract Study Objectives This study aims to evaluate the extent to which sleep quality
impacts amnestic mild cognitive impairment (aMCI)-related brain regions in a cognitively …

Dementia, a prevalent condition in the United States, affecting millions of individuals and
their families, underscores the importance of healthy cognitive ageing, which involves …

For centuries, sleep was considered a passive activity, perhaps even a period of time in life
that was a hindrance or barrier to getting more things accomplished. Although the exact …