The lung microbiome in carcinogenesis and immunotherapy treatment

K Kennedy, K Khaddour, N Ramnath… - The Cancer …, 2023 - journals.lww.com
Lung cancer is the leading cause of cancer-related deaths. Over the past 10 years,
significant advances in treatment modalities, including immune checkpoint inhibitor (ICI) …

Lung microbiome: An emerging player in lung cancer pathogenesis and progression

A Karvela, OZ Veloudiou, A Karachaliou… - Clinical and …, 2023 - Springer
The microbiome of the lungs, although until recently neglected, is now emerging as a
potential contributor to chronic lung diseases, including cancer. Preclinical evidence …

Understanding microbiome effect on immune checkpoint inhibition in lung cancer: placing the puzzle pieces together

U Swami, Y Zakharia, J Zhang - Journal of Immunotherapy, 2018 - journals.lww.com
Over the past couple of years, human microbiome has received increasing attention as a
regulator and predictor of response to the therapies of various diseases. It is speculated that …

Microbiota and lung cancer. opportunities and challenges for improving immunotherapy efficacy

M Ocáriz-Díez, M Cruellas, M Gascón, R Lastra… - Frontiers in …, 2020 - frontiersin.org
The advances in molecular biology and the emergence of Next Generation Sequencing
(NGS) have revealed that microbiome composition is closely related with health and …

The lung microbiota and lung cancer: a growing relationship

M Bou Zerdan, J Kassab, P Meouchy, E Haroun… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, the microbiota has emerged as a major player in
cancer management. The efficacy of chemotherapy or immunotherapy may be influenced by …

Gut microbiome and response to checkpoint inhibitors in non-small cell lung cancer—A review

M Nagasaka, R Sexton, R Alhasan, S Rahman… - Critical Reviews in …, 2020 - Elsevier
The gut microbiome is a collection of diverse bacteria that normally reside within the
gastrointestinal tract. In recent years, the relationship between the gut microbiome, and …

The lung microbiome: a central mediator of host inflammation and metabolism in lung cancer patients?

F Weinberg, RP Dickson, D Nagrath, N Ramnath - Cancers, 2020 - mdpi.com
Simple Summary Lung cancer is the major cause of cancer related deaths in the world. New
therapies have improved outcomes. Unfortunately, overall 5 year survival is~ 20 …

Microbiome: a supportive or a leading actor in lung cancer?

D Martins, F Mendes, F Schmitt - Pathobiology, 2021 - karger.com
Lung cancer is still the leading cause of cancer death worldwide. Despite the major
diagnostic and therapeutic innovations, the effect on mortality has been modest and the …

The gut microbiome from a biomarker to a novel therapeutic strategy for immunotherapy response in patients with lung cancer

S Duttagupta, T Hakozaki, B Routy, M Messaoudene - Current Oncology, 2023 - mdpi.com
The gastrointestinal microbiome has been shown to play a key role in determining the
responses to cancer immunotherapy, including immune checkpoint inhibitor (ICI) therapy …

The role of the microbiome in cancer and therapy efficacy: focus on lung cancer

A Halley, A Leonetti, A Gregori, M Tiseo… - Anticancer …, 2020 - ar.iiarjournals.org
The microbiome is extremely important for human health; more recently its role in the context
of cancer became clear. Microbial effects range from enhancing cancer immunity and cancer …