Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS

L Liu, JR Huh, K Shah - EBioMedicine, 2022 - thelancet.com
The recent revelation that the gut microbiome, home to approximately 100 trillion
microorganisms, is implicated in the development of both health and disease has spurred an …

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Convergent pathways of the gut microbiota–brain axis and neurodegenerative disorders

C Gubert, J Gasparotto, L H. Morais - Gastroenterology Report, 2022 - academic.oup.com
Recent research has been uncovering the role of the gut microbiota for brain health and
disease. These studies highlight the role of gut microbiota on regulating brain function and …

The microbiota-gut-brain axis in health and disease and its implications for translational research

MA Schächtle, SP Rosshart - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Over the past decades, microbiome research has evolved rapidly and became a hot topic in
basic, preclinical and clinical research, for the pharmaceutical industry and for the general …

Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis

Q Ma, C Xing, W Long, HY Wang, Q Liu… - Journal of …, 2019 - Springer
Abstract Development of central nervous system (CNS) is regulated by both intrinsic and
peripheral signals. Previous studies have suggested that environmental factors affect …

Implications of gut microbiota in neurodegenerative diseases

H Zhang, Y Chen, Z Wang, G Xie, M Liu… - Frontiers in …, 2022 - frontiersin.org
The morbidity associated with neurodegenerative diseases (NDs) is increasing, posing a
threat to the mental and physical quality of life of humans. The crucial effect of microbiota on …

Implications of the human gut–brain and gut–cancer axes for future nanomedicine

I Javed, X Cui, X Wang, M Mortimer, N Andrikopoulos… - ACS …, 2020 - ACS Publications
Recent clinical and pathological evidence have implicated the gut microbiota as a nexus for
modulating the homeostasis of the human body, impacting conditions from cancer and …

Human gut-microbiota interaction in neurodegenerative disorders and current engineered tools for its modeling

FA Ceppa, L Izzo, L Sardelli, I Raimondi… - Frontiers in cellular …, 2020 - frontiersin.org
The steady increase in life-expectancy of world population, coupled to many genetic and
environmental factors (for instance, pre-and post-natal exposures to environmental …

The gut microbiota–brain axis in behaviour and brain disorders

LH Morais, HL Schreiber IV… - Nature Reviews …, 2021 - nature.com
In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …

Microbiota-brain-gut axis and neurodegenerative diseases

EMM Quigley - Current neurology and neuroscience reports, 2017 - Springer
Abstract Purpose of Review The purposes of this review were as follows: first, to provide an
overview of the gut microbiota and its interactions with the gut and the central nervous …