[HTML][HTML] Coronaviruses, cholesterol and statins: Involvement and application for Covid-19

S Orlowski, JJ Mourad, A Gallo, E Bruckert - Biochimie, 2021 - Elsevier
The infectious power of coronaviruses is dependent on cholesterol present in the
membranes of their target cells. Indeed, the virus enters the infected cell either by fusion or …

The constellation of cholesterol-dependent processes associated with SARS-CoV-2 infection

FJ Barrantes - Progress in lipid research, 2022 - Elsevier
The role of cholesterol in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and other coronavirus-host cell interactions is currently being discussed in the context of two …

Commentary: statins, COVID-19, and coronary artery disease: killing two birds with one stone

S Ganjali, V Bianconi, PE Penson… - Metabolism …, 2020 - metabolismjournal.com
Although various pharmacologic agents are under active study [1], there are currently no
effective and evidence-based antiviral drugs or drug combinations against severe acute …

Statins as an adjunctive therapy for COVID-19: the biological and clinical plausibility

T Kashour, R Halwani, YM Arabi… - …, 2021 - Taylor & Francis
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes the
coronavirus disease 2019 (COVID-19) has infected millions of individuals and has claimed …

[HTML][HTML] Plausible positive effects of statins in covid-19 patient

A Vitiello, F Ferrara - Cardiovascular Toxicology, 2021 - Springer
Since the onset of the global COVID-19 pandemic, there has been much discussion about
the advantages and disadvantages of ongoing chronic drug therapies in SARS-CoV-2 …

[HTML][HTML] Statins in COVID-19 therapy

J Olszewska-Parasiewicz, Ł Szarpak, S Rogula… - Life, 2021 - mdpi.com
Inhibitors of 3-hydroxy-3methylgultaryl-coenzyme A reductase (statins) are one of the main
groups of drugs used in preventing and treating cardiovascular diseases worldwide. They …

[HTML][HTML] Statins in COVID-19: a new ray of hope

S Kunal, K Gupta, S Gupta - Heart & Lung, 2020 - ncbi.nlm.nih.gov
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) has spread around the world like a wildfire in the past six …

Cholesterol, lipoproteins, and COVID-19: Basic concepts and clinical applications

E Kočar, T Režen, D Rozman - … et Biophysica Acta (BBA)-Molecular and …, 2021 - Elsevier
Cholesterol is being recognized as a molecule involved in regulating the entry of the SARS-
CoV-2 virus into the host cell. However, the data about the possible role of cholesterol …

[HTML][HTML] COVID-19: direct and indirect mechanisms of statins

A Pawlos, M Niedzielski, P Gorzelak-Pabiś… - International Journal of …, 2021 - mdpi.com
The virus responsible for the current COVID-19 pandemic is severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2): a new virus with high infectivity and moderate …

Statins in coronavirus outbreak: It's time for experimental and clinical studies

M Bifulco, P Gazzerro - Pharmacological Research, 2020 - ncbi.nlm.nih.gov
Taking into account the SARS-coronavirus 2 (SARS-CoV-2 also know as COVID-19)
spreading and invasiveness in this critic period and the lack of therapeutic drugs and …