Total and free testosterone levels decline in men with advancing age due to defects at all
levels of the hypothalamic-pituitary-testicular axis. Age-related decline in total and free …

The only indication for testosterone administration in older men is testosterone replacement
therapy for male hypogonadism. Compared with young hypogonadal men, the diagnosis …

The substantial increase in life expectancy of men has focused growing attention on quality-
of-life issues associated with reproductive aging. Serum total and free testosterone levels in …

As men age, their serum testosterone concentration falls, the total testosterone concentration
barely but the free testosterone concentration more so. Testosterone treatment of older men …

In male mammals, changes at all levels of the hypothalamic-pituitary-testicular axis,
including alterations in the GnRH pulse generator, gonadotropin secretion, and testicular …

The decrease in testosterone levels with age is both central (pituitary) and peripheral
(testicular) origin. Because serum levels of sex-hormone-binding globulin increase with …

Testosterone levels decrease with normal aging, and researchers estimate that more than
4.5 million American men may have symptoms related to low testosterone. Termed late …

Testosterone deficiency is common in aging men and is associated not only with decreased
libido and sexual functioning but also with the aging process and quality of life. This article …

Testosterone plays an important role in maintaining both physical and mental function. Age‐
related testosterone depletion contributes to the development of angina, arteriosclerosis …

Increased longevity and population aging will increase the number of men with late onset
hypogonadism. It is a common condition, but often underdiagnosed and undertreated. The …