[HTML][HTML] SARS-CoV-2 infection of airway epithelial cells

G Ryu, HW Shin - Immune network, 2021 - ncbi.nlm.nih.gov
Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has been spreading worldwide since its outbreak in December 2019, and …

ACE2 expression is increased in the lungs of patients with comorbidities associated with severe COVID-19

BGG Pinto, AER Oliveira, Y Singh… - The Journal of …, 2020 - academic.oup.com
Patients who died from COVID-19 often had comorbidities, such as hypertension, diabetes,
and chronic obstructive lung disease. Although angiotensin-converting enzyme 2 (ACE2) is …

SARS-CoV-2, ACE2 expression, and systemic organ invasion

UM Ashraf, AA Abokor, JM Edwards… - Physiological …, 2021 - journals.physiology.org
A novel coronavirus disease, COVID-19, has created a global pandemic in 2020, posing an
enormous challenge to healthcare systems and affected communities. COVID-19 is caused …

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity

Z Inde, BA Croker, C Yapp, GN Joshi, J Spetz… - Science …, 2021 - science.org
Novel coronavirus disease 2019 (COVID-19) severity is highly variable, with pediatric
patients typically experiencing less severe infection than adults and especially the elderly …

[HTML][HTML] A dramatic rise in serum ACE2 activity in a critically ill COVID-19 patient

B Nagy Jr, Z Fejes, Z Szentkereszty, R Sütő… - International Journal of …, 2021 - Elsevier
Endothelial cells express surface angiotensin-converting enzyme 2 (ACE2), the main
receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that promotes …

Systematic profiling of ACE2 expression in diverse physiological and pathological conditions for COVID‐19/SARS‐CoV‐2

Y Li, Q Xu, L Ma, D Wu, J Gao… - Journal of cellular and …, 2020 - Wiley Online Library
Recent retrospective studies of severe acute respiratory syndrome coronavirus 2 (SARS‐
CoV‐2) disease (COVID‐19) revealed that the patients with common comorbidities of …

The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2

L Chen, X Li, M Chen, Y Feng… - Cardiovascular research, 2020 - academic.oup.com
A new type of pneumonia caused by a novel coronavirus SARS-CoV-2 outbreaks recently in
China and spreads into many other countries. This disease, named as COVID-19, is similar …

A systemic and molecular study of subcellular localization of SARS-CoV-2 proteins

J Zhang, R Cruz-Cosme, MW Zhuang, D Liu… - Signal transduction and …, 2020 - nature.com
The current pandemic of beta-coronavirus (SARS-CoV-2) has exerted devastating influence
on almost all countries, resulting in the disease named COVID-19. 1 Coronavirus possesses …

Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2

L Wu, Q Chen, K Liu, J Wang, P Han, Y Zhang, Y Hu… - Cell discovery, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the
recent pandemic COVID-19, is reported to have originated from bats, with its intermediate …

[HTML][HTML] The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes

H Zhang, Z Kang, H Gong, D Xu, J Wang, Z Li, X Cui… - BioRxiv, 2020 - biorxiv.org
Since December 2019, a newly identified coronavirus (2019 novel coronavirus, 2019-nCov)
is causing outbreak of pneumonia in one of largest cities, Wuhan, in Hubei province of …