Degrading vision by one eye during a developmental critical period yields enduring deficits
in both eye dominance and visual acuity. A predominant model is that" reactivating" ocular …

The closure of developmental critical periods consolidates neural circuitry but also limits
recovery from early abnormal sensory experience. Degrading vision by one eye throughout …

A characteristic of the developing mammalian visual system is a brief interval of plasticity,
termed the “critical period,” when the circuitry of primary visual cortex is most sensitive to …

The formation and stability of dendritic spines on excitatory cortical neurons are correlated
with adult visual plasticity, yet how the formation, loss, and stability of postsynaptic spines …

During the developmental critical period for visual plasticity, discordant vision alters the
responsiveness of neurons in visual cortex. The subsequent closure of the critical period not …

Binocular matching of orientation preference between the two eyes is a common form of
binocular integration that is regarded as the basis for stereopsis. How critical period …

Disrupting binocular vision during a developmental critical period can yield enduring
changes to ocular dominance (OD) in primary visual cortex (V1). Here we investigated how …

Monocular deprivation normally alters ocular dominance in the visual cortex only during a
postnatal critical period (20 to 32 days postnatal in mice). We find that mutations in the Nogo …

The shift in ocular dominance (OD) of binocular neurons induced by monocular deprivation
is the canonical model of synaptic plasticity confined to a postnatal critical period …

Amblyopia is difficult to cure in adult due to the declination of visual cortical plasticity with
age. However, the mechanisms limiting adult cortical plasticity are still unclear. Inhibition …