Bioaerosol sampling of patients with suspected pulmonary tuberculosis: a study protocol

B Patterson, A Koch, S Gessner, R Dinkele… - BMC infectious …, 2020 - Springer
Background Tuberculosis (TB) is transmitted in bioaerosols containing Mycobacterium
tuberculosis (Mtb). Despite being central to ongoing TB transmission, no routine diagnostic …

Sensitivity optimisation of tuberculosis bioaerosol sampling

B Patterson, R Dinkele, S Gessner, C Morrow… - PLoS …, 2020 - journals.plos.org
Introduction Detection of Mycobacterium tuberculosis (Mtb) in patient-derived bioaerosol is a
potential tool to measure source case infectiousness. However, current bioaerosol sampling …

Detection of Mycobacterium tuberculosis bacilli in bio-aerosols from untreated TB patients

B Patterson, C Morrow, V Singh, A Moosa… - Gates open …, 2018 - pmc.ncbi.nlm.nih.gov
Background: Tuberculosis (TB) is predominantly an airborne disease. However, quantitative
and qualitative analysis of bio-aerosols containing the aetiological agent, Mycobacterium …

[HTML][HTML] Detection of Mycobacterium tuberculosis RNA in bioaerosols from pulmonary tuberculosis patients

A Shaikh, K Sriraman, S Vaswani, V Oswal… - International Journal of …, 2019 - Elsevier
Background Bioaerosols from pulmonary tuberculosis (PTB) patients are a quantitative
predictor of transmission. Current methods involve sophisticated instruments and time …

Aerosolization of viable Mycobacterium tuberculosis bacilli by tuberculosis clinic attendees independent of sputum-Xpert Ultra status

B Patterson, R Dinkele, S Gessner… - Proceedings of the …, 2024 - National Acad Sciences
Potential Mycobacterium tuberculosis (Mtb) transmission during different pulmonary
tuberculosis (TB) disease states is poorly understood. We quantified viable aerosolized Mtb …

[HTML][HTML] Persistent Mycobacterium tuberculosis bioaerosol release in a tuberculosis-endemic setting

R Dinkele, S Gessner, B Patterson, A McKerry… - medRxiv, 2024 - ncbi.nlm.nih.gov
Pioneering studies linking symptomatic disease and cough-mediated release of
Mycobacterium tuberculosis (Mtb) established the infectious origin of tuberculosis (TB) …

Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis patient bioaerosols

R Dinkele, S Gessner, A McKerry, B Leonard… - PLoS …, 2021 - journals.plos.org
Interrupting transmission is an attractive anti-tuberculosis (TB) strategy but it remains
underexplored owing to our poor understanding of the events surrounding transfer of …

Development and evaluation of a rapid molecular assay and a mask sampling method enabling the study of tuberculosis transmission

ESG Cheah - 2010 - figshare.le.ac.uk
Mycobacterium tuberculosis (Mtb) is transmitted in small aerosol droplets expectorated by
individuals with active pulmonary tuberculosis (TB). There is still no established method for …

[HTML][HTML] Cough-independent production of viable Mycobacterium tuberculosis in bioaerosol

B Patterson, W Bryden, C Call, A McKerry, B Leonard… - Tuberculosis, 2021 - Elsevier
Background Symptoms of infectious respiratory illnesses are often assumed to drive
transmission. However, production and release of Mycobacterium tuberculosis (Mtb) …

Non-invasive approach to diagnosis of pulmonary tuberculosis using microdroplets collected from exhaled air

VN Morozov, AA Nikolaev… - Journal of breath …, 2018 - iopscience.iop.org
In this report we present a proof-of-principle study aimed at developing non-invasive
diagnostics for pulmonary TB that are based on analyzing TB biomarkers in exhaled …