Biomarker-based guideline-directed medical therapy of heart failure: the gap between guidelines and clinical practice

AE Berezin, AA Berezin - 2021 - dspace.zsmu.edu.ua
Current clinical recommendations provided by the 2016 European Society of Cardiology
(ESC) and 2017 American College of Cardiology (ACC)/American Heart Association …

The role of biomarkers in the prognosis and risk stratification in heart failure: A systematic review

G Singh, H Bamba, P Inban, SH Chandrasekaran… - Disease-a-Month, 2024 - Elsevier
Acute heart failure (AHF) episodes are marked by high rates of morbidity and mortality
during the episode and minimal advancements in its care. Multiple biomarker monitoring is …

UMBRELLA protocol: systematic reviews of multivariable biomarker prognostic models developed to predict clinical outcomes in patients with heart failure

MDLA Vazquez-Montes, TPA Debray, KS Taylor… - … and prognostic research, 2020 - Springer
Background Heart failure (HF) is a chronic and common condition with a rising prevalence,
especially in the elderly. Morbidity and mortality rates in people with HF are similar to those …

Do Heart Failure Biomarkers Influence Heart Failure Treatment Response?

T Yuen, P Gouda, R Margaryan, J Ezekowitz - Current Heart Failure …, 2023 - Springer
Abstract Purpose of Review Heart failure (HF) is one of the leading causes of cardiac
morbidity and mortality around the world. Our evolving understanding of the cellular and …

Biomarker-guided versus guideline-based treatment of patients with heart failure: results from BIOSTAT-CHF

W Ouwerkerk, AH Zwinderman, LL Ng… - Journal of the American …, 2018 - jacc.org
Background: Heart failure guidelines recommend up-titration of angiotensin-converting
enzyme (ACE) inhibitor/angiotensin receptor blockers (ARBs), beta-blockers, and …

Biomarkers in heart failure: the past, current and future

M Sarhene, Y Wang, J Wei, Y Huang, M Li, L Li… - Heart failure …, 2019 - Springer
Despite the enhanced knowledge of the pathophysiology of heart failure (HF), it still remains
a serious syndrome with substantial morbidity, mortality, and frequent hospitalizations …

Biomarkers in heart failure clinical trials. A review from the Biomarkers Working Group of the Heart Failure Association of the European Society of Cardiology

A Bayes‐Genis, A Aimo, P Jhund… - European Journal of …, 2022 - Wiley Online Library
The approval of new heart failure (HF) therapies has slowed over the past two decades in
part due to the high costs of conducting large randomized clinical trials that are needed to …

Beyond Natriuretic Peptides: Unveiling the Power of Emerging Biomarkers in Heart Failure

R Licordari, M Correale, S Bonanno, M Beltrami… - Biomolecules, 2024 - mdpi.com
Heart failure (HF) represents a significant global health challenge, characterized by high
morbidity and mortality rates, and imposes considerable burdens on healthcare systems and …

Clinical factors related to morbidity and mortality in high‐risk heart failure patients: the GUIDE‐IT predictive model and risk score

C O'Connor, M Fiuzat, H Mulder, A Coles… - European journal of …, 2019 - Wiley Online Library
Background Most heart failure (HF) risk scores have been derived from cohorts of stable HF
patients and may not incorporate up to date treatment regimens or deep phenotype …

The future of biomarker-guided therapy for heart failure after the guiding evidence-based therapy using biomarker intensified treatment in heart failure (GUIDE-IT) …

NE Ibrahim, JL Januzzi - Current Heart Failure Reports, 2018 - Springer
Abstract Purpose of Review Biomarker-guided management of patients with chronic heart
failure with reduced ejection fraction (HFrEF) remains controversial. Recent Findings …