Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

Healthy aging is associated with declines in episodic memory. This reduction is thought to
be due in part to age-related differences in encoding-related processes. In the current study …

Episodic memories are established and maintained by close interplay between
hippocampus and other cortical regions, but degradation of a fronto-striatal network has …

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder, rapidly increasing in
prevalence as the population ages. As the potential for disease-modifying therapy grows, a …

Emerging studies have emphasized the importance of the fidelity of cortical representation in
forming enduring episodic memory. No study, however, has examined whether there are …

Lesion studies have shown convincingly that the medial temporal lobes (MTL) and frontal
lobes are critical to episodic memory. Ageing generally has been found to have a generally …

Surprisingly little is known about the neural correlates of remembering real life events in the
context of normal aging. We therefore asked young and older adults to retrieve real life …

We used fMRI to assess the neural correlates of autobiographical, semantic, and episodic
memory retrieval in healthy young and older adults. Participants were tested with an event …

The clinical hallmark of Alzheimer's disease (AD) is a gradual decline in cognitive function.
For the majority of patients the initial symptom is an impairment in episodic memory, ie, the …

Aging is associated with declines in episodic memory. In this study, the authors used a path
analysis framework to explore the mediating role of differences in brain structure, executive …