Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …

Abstract Development and progression of cancer are mediated by alterations in
transcriptional networks, resulting in a disturbed balance between the activity of oncogenes …

SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and
contains a high-mobility group (HMG) domain, which permits highly specific DNA binding …

Gastric cancer (GC) is a leading cause of death worldwide. GC is the third-most common
cause of cancer-related death after lung and colorectal cancer. It is also the fifth-most …

Sox4, Sox11 and Sox12 constitute the group C of Sry-related HMG box proteins. They are co-
expressed in embryonic neuronal progenitors and in mesenchymal cells in many …

SOX4 is an essential developmental transcription factor that regulates stemness,
differentiation, progenitor development, and multiple developmental pathways including …

SOX2 is a well-characterized pluripotent factor that is essential for stem cell self-renewal,
reprogramming, and homeostasis. The cellular levels of SOX2 are precisely regulated by a …

The pluripotency-associated transcription factor SOX2 is essential during mammalian
embryogenesis and later in life, but SOX2 expression can also be highly detrimental. Over …

The transcription factor SOX2 is essential for embryonic development and plays a crucial
role in maintaining the stemness of embryonic cells and various adult stem cell populations …

Sex-determining region Y-related (SRY) high-mobility group box 4 (SOX4) is a member of
the group C subfamily of SOX transcription factors and promotes tumorigenesis by endowing …