Wnt genes and β-Catenin signaling are involved in axial patterning processes in vertebrate
embryogenesis in setting up the Spemann–Mangold organizer in amphibian embryos. An …

Polyps of the cnidarian Hydra maintain their adult anatomy through two developmental
organizers, the head organizer located apically and the foot organizer basally. The head …

In an adult hydra the head organizer, located in the hypostome, is constantly active in
maintaining the structure of the animal in the context of its steady state tissue dynamics …

Members of the Wnt/wingless family of secreted proteins act as short-range inducers and
long-range organizers during axis formation, organogenesis and tumorigenesis in many …

We studied the role of Wnt signaling in axis formation during metamorphosis and
regeneration in the cnidarian Hydractinia. Activation of Wnt downstream events during …

Wnt/β-Catenin signaling plays crucial roles in regenerative processes in eumetazoans. It
also acts in regeneration and axial patterning in the simple freshwater polyp Hydra, whose …

Decapitated Hydra regenerate their heads via morphallaxis, ie, without significant
contributions made by cell proliferation or interstitial stem cells. Indeed, Hydra depleted of …

In and evaginations of 2D cell sheets are major shape generating processes in animal
development. They result from directed movement and intercalation of polarized cells …

Stabilization of β-catenin by inhibiting the activity of glycogen synthase kinase-3β has been
shown to initiate axis formation or axial patterning processes in many bilaterians. In hydra …

Morphogen gradients play an important role in pattern formation during early stages of
embryonic development in many bilaterians. In an adult hydra, axial patterning processes …