Encapsulation of therapeutic molecules into nanocarrier is an extensively explored strategy
to treat cancer more effectively. In this study, pH-responsive targeting dual-agent delivery …

The aim of this study was to design and develop a new pH-responsive nano-platform for
controlled and targeted delivery of anticancer drugs. Engineering of pH-responsive …

Synthesis of amphiphilic poly (β-amino esters)(PBAE) was optimized by stepwise feeding of
monomers (PBAE-(PH)) compared with one-pot synthesis (PBAE-(P&H)) based on poly …

Although various nanocarriers have been developed to deliver anticancer drugs to the target
tumors, it is still remaining great challenges, including burst release, non-specific …

Co-delivery of multiple drugs with complementary anticancer mechanisms by nano-carriers
offers an effective strategy to treat cancer. The combination of drugs with pro-apoptotic and …

A limitation of current anticancer nanocarriers is the contradiction between multiple functions
and favorable biocompatibility. Thus, we aimed to develop a compatible drug delivery …

In this study, a new type of polypeptide, crosslinked methoxy poly (ethylene glycol)-g-poly
(aspartic acid)-g-tyrosine (CPPT), was synthesized via a green and simple one-pot …

As the tumor microenvironment (TME) develops, it is critical to take the alterations of pH
value, reduction and various enzymes of the TME into consideration when constructing the …

Amphiphilic core–shell (ACS) nanoparticles are gaining increasing research interest for
multi-drug delivery in cancer therapy. In this work, a new cationic peptide-coated PHA …

Abstract pH-Responsive nanoparticles (NPs) have emerged as an effective antitumor drug
delivery system, promoting the drugs accumulation in the tumor and selectively releasing …