Catalytic hairpin assembly-based electrochemical biosensor with tandem signal amplification for sensitive microRNA assay

L Cui, J Zhou, XY Yang, J Dong, X Wang… - Chemical …, 2020 - pubs.rsc.org
We demonstrate for the first time the construction of a low background electrochemical
biosensor with tandem signal amplification for sensitive microRNA assay based on target …

Mismatched catalytic hairpin assembly and ratiometric strategy for highly sensitive electrochemical detection of microRNA from tumor cells

X Li, B Dou, R Yuan, Y Xiang - Sensors and Actuators B: Chemical, 2019 - Elsevier
MicroRNAs (miRNAs) are regarded as promising biomarkers for the prognosis, diagnosis
and treatment of different cancers. However, resulting from their low abundance, short length …

Peptide nucleic acid-based electrochemical biosensor for simultaneous detection of multiple microRNAs from cancer cells with catalytic hairpin assembly amplification

P Fu, S Xing, M Xu, Y Zhao, C Zhao - Sensors and Actuators B: Chemical, 2020 - Elsevier
Herein we demonstrated a facile electrochemical method for simultaneous detection of
miRNA21 and miRNA155 using a peptide nucleic acids (PNAs)-modified gold electrode …

A simple electrochemical biosensor for highly sensitive and specific detection of microRNA based on mismatched catalytic hairpin assembly

Y Zhang, Y Yan, W Chen, W Cheng, S Li, X Ding… - Biosensors and …, 2015 - Elsevier
MicroRNAs (miRNAs) play vital regulatory roles in cancer development and a variety of
diseases, which make them become promising biomarkers. Here, a simple electrochemical …

Double-loop hairpin probe and doxorubicin-loaded gold nanoparticles for the ultrasensitive electrochemical sensing of microRNA

Y Tao, D Yin, M Jin, J Fang, T Dai, Y Li, Y Li… - Biosensors and …, 2017 - Elsevier
An electrochemical microRNA (miRNA) analysis platform by combining double-loop hairpin
probe (DHP) and doxorubicin-loaded gold nanoparticles (AuNPs@ Dox) for ultrasensitive …

A highly sensitive and robust electrochemical biosensor for microRNA detection based on PNA-DNA hetero-three-way junction formation and target-recycling catalytic …

X Yu, S Ding, Y Zhao, M Xu, Z Wu, C Zhao - Talanta, 2024 - Elsevier
Robust and sensitive methods for the detection of microRNAs (miRNAs) are crucial in the
clinical diagnosis of cancers. In this study, a novel electrochemical biosensor with high …

Sensitive detection of microRNAs using hemin/G-quadruplex concatamers as trace labels and RNA endonuclease-aided target recycling for amplification

G Xiang, D Jiang, F Luo, F Liu, L Liu, X Pu - Sensors and Actuators B …, 2014 - Elsevier
In this work, a novel electrochemical biosensor based on endonuclease-aided target
recycling and hybridization chain reaction (HCR) was constructed for the sensitive detection …

A reusable microRNA sensor based on the electrocatalytic property of heteroduplex-templated copper nanoclusters

Z Wang, L Si, J Bao, Z Dai - Chemical Communications, 2015 - pubs.rsc.org
DNA–RNA heteroduplexes have been used as templates for copper nanocluster (CuNC)
formation for the first time. Taking advantage of the electrocatalysis of CuNCs, quantitation of …

Label-free and enzyme-free homogeneous electrochemical biosensing strategy based on hybridization chain reaction: A facile, sensitive, and highly specific …

T Hou, W Li, X Liu, F Li - Analytical chemistry, 2015 - ACS Publications
Homogenous electrochemical biosensing strategies have attracted substantial attention,
because of their advantages of being immobilization-free and having rapid response and …

3D DNA nanonet structure coupled with target-catalyzed hairpin assembly for dual-signal synergistically amplified electrochemical sensing of circulating microRNA

W Zhang, H Xu, X Zhao, X Tang, S Yang, L Yu… - Analytica Chimica …, 2020 - Elsevier
DNA nanomaterials are reliable and powerful tools in the development of a variety of
biosensors owing to their notable self-assembly ability and precise recognition capability …