Background and aims The lipid profile is consistently associated with coronary artery
disease (CAD) and ischemic stroke (IS). However, the lipoprotein subfractions have not …

Circulating lipids and changes in lipid profiles have long been associated with the
development of stroke but causal relationships remain unclear. In this study, we aimed to …

Objective We conducted a Mendelian randomization (MR) study to disentangle the
comparative effects of lipids and apolipoproteins on ischemic stroke. Methods Single …

Background and Objectives Cerebral small vessel disease is a major cause of stroke and
dementia. Metabolomics can help identify novel risk factors to better understand …

Background and purpose Circulating metabolites have been implicated in stroke
pathogenesis, but their genetic determinants are understudied. Using a Mendelian …

Background and purpose The associations of lipid profiles with the risk of ischemic stroke
(IS) or hemorrhagic stroke (HS) are controversial. In this study, we aimed to illustrate the …

Background and Purpose—Statin therapy is associated with a lower risk of ischemic stroke
supporting a causal role of low-density lipoprotein (LDL) cholesterol. However, more …

Aims An increasing number of studies on non-traditional lipid profiles have been
investigated in recent years. However, the associations between non-traditional lipid profiles …

Background Stroke is a leading cause of death worldwide, but it is unclear whether
circulating lipids and lipid-lowering drugs are causally associated with stroke and its …

Background Cerebral small vessel disease is a major cause of ischemic stroke and vascular
dementia, which are among the leading causes of death and disability worldwide …