Analyzing the loss and the recovery of consciousness: functional connectivity patterns and changes in heart rate variability during propofol-induced anesthesia

D Sattin, D Duran, S Visintini, E Schiaffi… - Frontiers in systems …, 2021 - frontiersin.org
The analysis of the central and the autonomic nervous systems (CNS, ANS) activities during
general anesthesia (GA) provides fundamental information for the study of neural processes …

Network properties in transitions of consciousness during propofol-induced sedation

M Lee, RD Sanders, SK Yeom, DO Won, KS Seo… - Scientific reports, 2017 - nature.com
Reliable electroencephalography (EEG) signatures of transitions between consciousness
and unconsciousness under anaesthesia have not yet been identified. Herein we examined …

Dynamic local connectivity uncovers altered brain synchrony during propofol sedation

RD Bharath, R Panda, J Saini, K Sriganesh… - Scientific Reports, 2017 - nature.com
Human consciousness is considered a result of the synchronous “humming” of multiple
dynamic networks. We performed a dynamic functional connectivity analysis using resting …

Detecting loss and regain of consciousness during propofol anesthesia using multimodal indices of autonomic state

S Subramanian, R Barbieri, PL Purdon… - 2020 42nd Annual …, 2020 - ieeexplore.ieee.org
We have traditionally definedloss of consciousness'(LOC) andregain of
consciousness'(ROC) during general anesthesia in terms of behavioral correlates. We are …

Paradoxical markers of conscious levels: Effects of propofol on patients in disorders of consciousness

C Maschke, C Duclos, S Blain-Moraes - Frontiers in Human …, 2022 - frontiersin.org
Human consciousness is widely understood to be underpinned by rich and diverse
functional networks, whose breakdown results in unconsciousness. Candidate neural …

The thalamus and brainstem act as key hubs in alterations of human brain network connectivity induced by mild propofol sedation

T Gili, N Saxena, A Diukova, K Murphy… - Journal of …, 2013 - Soc Neuroscience
Despite their routine use during surgical procedures, no consensus has yet been reached
on the precise mechanisms by which hypnotic anesthetic agents produce their effects …

Diversity of functional connectivity patterns is reduced in propofol‐induced unconsciousness

H Lee, GJ Noh, P Joo, BM Choi… - Human Brain …, 2017 - Wiley Online Library
Introduction Recent evidence suggests that the conscious brain is characterized by a
diverse repertoire of functional connectivity patterns while the anesthetized brain shows …

Spatiotemporal reconfiguration of large-scale brain functional networks during propofol-induced loss of consciousness

MS Schröter, VI Spoormaker, A Schorer… - Journal of …, 2012 - Soc Neuroscience
Applying graph theoretical analysis of spontaneous BOLD fluctuations in functional
magnetic resonance imaging (fMRI), we investigated whole-brain functional connectivity of …

Exploring the neural basis of consciousness through anesthesia

S Shushruth - Journal of Neuroscience, 2013 - Soc Neuroscience
Anesthetics are among the most widely used drugs affecting the CNS. While we have a
reasonable understanding of the pharmacological effects of anesthetics (Brown et al., 2011) …

Information integration and mesoscopic cortical connectivity during propofol anesthesia

Z Liang, L Cheng, S Shao, X Jin, T Yu, JW Sleigh… - …, 2020 - pubs.asahq.org
Background The neurophysiologic mechanisms of propofol-induced loss of consciousness
have been studied in detail at the macro (scalp electroencephalogram) and micro (spiking or …