Health implications of high dietary omega‐6 polyunsaturated fatty acids

E Patterson, R Wall, GF Fitzgerald… - Journal of nutrition …, 2012 - Wiley Online Library
Omega‐6 (n‐6) polyunsaturated fatty acids (PUFA)(eg, arachidonic acid (AA)) and omega‐3
(n‐3) PUFA (eg, eicosapentaenoic acid (EPA)) are precursors to potent lipid mediator …

Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance—A review

RK Saini, YS Keum - Life sciences, 2018 - Elsevier
Abstract Linoleic acid (LA)(n− 6) and α-linolenic acid (ALA)(n− 3) are essential fatty acids
(EFAs) as they cannot be synthesized by humans or other higher animals. In the human …

The opposing effects of n− 3 and n− 6 fatty acids

G Schmitz, J Ecker - Progress in lipid research, 2008 - Elsevier
Polyunsaturated fatty acids (PUFAs) can be classified in n− 3 fatty acids and n− 6 fatty acids,
and in westernized diet the predominant dietary PUFAs are n− 6 fatty acids. Both types of …

Overconsumption of Omega‐6 polyunsaturated fatty acids (PUFAs) versus deficiency of Omega‐3 PUFAs in modern‐day diets: the disturbing factor for their “balanced …

AH Mariamenatu, EM Abdu - Journal of lipids, 2021 - Wiley Online Library
Polyunsaturated fatty acids (PUFAs) contain≥ 2 double‐bond desaturations within the acyl
chain. Omega‐3 (n‐3) and Omega‐6 (n‐6) PUFAs are the two known important families in …

Significance of long chain polyunsaturated fatty acids in human health

R Zárate, N el Jaber-Vazdekis, N Tejera… - Clinical and translational …, 2017 - Springer
In the last decades, the development of new technologies applied to lipidomics has
revitalized the analysis of lipid profile alterations and the understanding of the underlying …

n− 3 Polyunsaturated fatty acids and inflammation: from molecular biology to the clinic

PC Calder - Lipids, 2003 - Wiley Online Library
The immune system is involved in host defense against infectious agents, tumor cells, and
environmental insults. Inflammation is an important component of the early immunologic …

Health benefits of n-3 polyunsaturated fatty acids: eicosapentaenoic acid and docosahexaenoic acid

N Siriwardhana, NS Kalupahana… - Advances in food and …, 2012 - Elsevier
Marine-based fish and fish oil are the most popular and well-known sources of n-3
polyunsaturated fatty acids (PUFAs), namely, eicosapentaenoic acid (EPA) and …

A review of recent evidence in human studies of n-3 and n-6 PUFA intake on cardiovascular disease, cancer, and depressive disorders: does the ratio really matter?

S Marventano, P Kolacz, S Castellano… - … journal of food …, 2015 - Taylor & Francis
Polyunsaturated fatty acids (PUFAs) have been considered of great interest for human
health due to their potential anti-inflammatory action that may protect from a number of …

N-3 polyunsaturated fatty acids: relationship to inflammation in healthy adults and adults exhibiting features of metabolic syndrome

LE Robinson, VC Mazurak - Lipids, 2013 - Springer
Individuals with metabolic syndrome (MetS) have a higher risk of type 2 diabetes and
cardiovascular disease, therefore, research has been directed at reducing various …

Pharmacology and therapeutics of omega-3 polyunsaturated fatty acids in chronic inflammatory disease

CM Yates, PC Calder, GE Rainger - Pharmacology & therapeutics, 2014 - Elsevier
Abstract Omega-3 (n− 3) polyunsaturated fatty acids (n− 3 PUFAs) have well documented
anti-inflammatory properties, and consequently therapeutic potential in chronic inflammatory …