Is there evidence for more than two diffusion components in abdominal organs?–A magnetic resonance imaging study in healthy volunteers

MC Wurnig, M Germann, A Boss - NMR in Biomedicine, 2018 - Wiley Online Library
The most commonly applied model for the description of diffusion‐weighted imaging (DWI)
data in perfused organs is bicompartmental intravoxel incoherent motion (IVIM) analysis. In …

Systematic analysis of the intravoxel incoherent motion threshold separating perfusion and diffusion effects: proposal of a standardized algorithm

MC Wurnig, OF Donati, E Ulbrich, L Filli… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose To systematically evaluate the dependence of intravoxel‐incoherent‐motion (IVIM)
parameters on the b‐value threshold separating the perfusion and diffusion compartment …

Intravoxel incoherent motion diffusion‐weighted MRI of the abdomen: the effect of fitting algorithms on the accuracy and reliability of the parameters

HJ Park, YS Sung, SS Lee, Y Lee… - Journal of Magnetic …, 2017 - Wiley Online Library
Purpose To evaluate the influence of fitting methods on the accuracy and reliability of
intravoxel incoherent motion (IVIM) parameters, with a particular emphasis on the constraint …

Extended T2-IVIM model for correction of TE dependence of pseudo-diffusion volume fraction in clinical diffusion-weighted magnetic resonance imaging

NP Jerome, JA d'Arcy, T Feiweier… - Physics in Medicine …, 2016 - iopscience.iop.org
The bi-exponential intravoxel-incoherent-motion (IVIM) model for diffusion-weighted MRI
(DWI) fails to account for differential T 2 s in the model compartments, resulting in …

Spatially-constrained probability distribution model of incoherent motion (SPIM) for abdominal diffusion-weighted MRI

S Kurugol, M Freiman, O Afacan… - Medical image …, 2016 - Elsevier
Quantitative diffusion-weighted MR imaging (DW-MRI) of the body enables characterization
of the tissue microenvironment by measuring variations in the mobility of water molecules …

A standardized parameter-free algorithm for combined intravoxel incoherent motion and diffusion kurtosis analysis of diffusion imaging data

MC Wurnig, D Kenkel, L Filli, A Boss - Investigative radiology, 2016 - journals.lww.com
Objectives The aims of this study were to implement and systematically evaluate the
performance of a new parameter-free segmented algorithm for analysis of diffusion imaging …

Evidence of tri-exponential decay for liver intravoxel incoherent motion MRI: a review of published results and limitations

O Chevallier, YXJ Wáng, K Guillen, J Pellegrinelli… - Diagnostics, 2021 - mdpi.com
Diffusion weighted imaging (DWI) and intravoxel incoherent motion (IVIM) have been
explored to assess liver tumors and diffused liver diseases. IVIM reflects the microscopic …

[HTML][HTML] Diffusion-weighted MRI of the liver: challenges and some solutions for the quantification of apparent diffusion coefficient and intravoxel incoherent motion

YXJ Wang, H Huang, CJ Zheng, BH Xiao… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Diffusion-weighted imaging (DWI) is sensitive to the mobility of water molecule at cellular
and macromolecular level, much smaller than the spatial resolution of the images. It is …

Perfusion assessment using intravoxel incoherent motion-based analysis of diffusion-weighted magnetic resonance imaging: validation through phantom experiments

JH Lee, H Cheong, SS Lee, CK Lee… - Investigative …, 2016 - journals.lww.com
Objectives The aims of this study were to demonstrate the theoretical meaning of intravoxel
incoherent motion (IVIM) parameters and to compare the robustness of 2 biexponential …

Limitations of apparent diffusion coefficient‐based models in characterizing non‐gaussian diffusion

C Liu, R Bammer, ME Moseley - Magnetic Resonance in …, 2005 - Wiley Online Library
Diffusion in complex heterogeneous structures, for example, the neural fiber system, is non‐
gaussian. Recently, several methods have been introduced to address the issue of non …