The mammalian striatum controls the output of the basal ganglia via two distinct efferent
pathways, the direct (ie, striatonigral) and the indirect (ie, striatopallidal) pathways. The LIM …

Striatal projection neurons comprise two populations of striatonigral and striatopallidal
neurons. These two neuronal populations play distinct roles in controlling movement-related …

LIM homeodomain transcription factors play crucial roles in determining diverse aspects of
neuronal development both in vertebrates and invertebrates. In the present study, we …

Forebrain cholinergic neurons modulate complex mammalian behaviors such as reward-
related learning and cognitive functions. Although their dysfunction is implicated in various …

We provide a detailed and exhaustive description of forebrain regions, nuclei, and neuronal
populations which express the LIM-homeodomain transcription factor Islet1 during Xenopus …

Recent studies have shown that the LIM-homeodomain transcription factor Isl1 is required
for the survival and differentiation of direct pathway striatonigral neurons during embryonic …

We have isolated the Drosophila homolog of the vertebrate islet-1 and islet-2 genes, two
members of the LIM homeodomain family implicated in the transcriptional control of motor …

Neurons in the hypothalamic arcuate nucleus relay and translate important cues from the
periphery into the central nervous system. However, the gene regulatory program directing …

The LIM homeodomain transcription factor Islet1 (Isl1) is expressed in multiple organs and
plays essential roles during embryogenesis. Isl1 is required for the survival and specification …

The generation and maintenance of a plethora of neuronal subtypes is essential for normal
brain function. Nevertheless, little is known about the molecular mechanisms that maintain …