Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain

V Tabar, G Panagiotakos, ED Greenberg… - Nature …, 2005 - nature.com
Human embryonic stem (hES) cells provide a potentially unlimited cell source for
regenerative medicine. Recently, differentiation strategies were developed to direct hES …

Human embryonic stem cell‐derived neural precursors develop into neurons and integrate into the host brain

DJ Guillaume, MA Johnson, XJ Li… - Journal of …, 2006 - Wiley Online Library
Whether and how in‐vitro‐produced human neural precursors mature and integrate into the
brain are crucial to the utility of human embryonic stem (hES) cells in treating neurological …

Neural progenitors from human embryonic stem cells

BE Reubinoff, P Itsykson, T Turetsky, MF Pera… - Nature …, 2001 - nature.com
The derivation of neural progenitor cells from human embryonic stem (ES) cells is of value
both in the study of early human neurogenesis and in the creation of an unlimited source of …

Neural precursors derived from human embryonic stem cells maintain long‐term proliferation without losing the potential to differentiate into all three neural lineages …

S Hong, UJ Kang, O Isacson… - Journal of …, 2008 - Wiley Online Library
Human embryonic stem (hES) cells have the ability to renew themselves and differentiate
into multiple cell types upon exposure to appropriate signals. In particular, the ability of hES …

A method for rapid derivation and propagation of neural progenitors from human embryonic stem cells

MZ Axell, S Zlateva, M Curtis - Journal of neuroscience methods, 2009 - Elsevier
Neuronal loss is a common feature of many neurological disorders, including stroke,
Parkinson's disease, Alzheimer's disease and traumatic brain injury. Human embryonic stem …

Neural differentiation of human ES cells

M A. Cohen, P Itsykson… - Current protocols in cell …, 2007 - Wiley Online Library
Human embryonic stem cells (hESCs) may be converted into highly enriched cultures of
neural precursors under defined culture conditions. The neural precursors can proliferate in …

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

SC Zhang, M Wernig, ID Duncan, O Brüstle… - Nature …, 2001 - nature.com
The remarkable developmental potential and replicative capacity of human embryonic stem
(ES) cells promise an almost unlimited supply of specific cell types for transplantation …

Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells

SH Lee, N Lumelsky, L Studer, JM Auerbach… - Nature …, 2000 - nature.com
Embryonic stem (ES) cells are clonal cell lines derived from the inner cell mass of the
developing blastocyst that can proliferate extensively in vitro and are capable of adopting all …

Derivation of midbrain dopamine neurons from human embryonic stem cells

AL Perrier, V Tabar, T Barberi… - Proceedings of the …, 2004 - National Acad Sciences
Human embryonic stem (hES) cells are defined by their extensive self-renewal capacity and
their potential to differentiate into any cell type of the human body. The challenge in using …

Neurogenic neuroepithelial and radial glial cells generated from six human embryonic stem cell lines in serum‐free suspension and adherent cultures

R Nat, M Nilbratt, S Narkilahti, B Winblad, O Hovatta… - Glia, 2007 - Wiley Online Library
The great potential of human embryonic stem (hES) cells offers the opportunity both for
studying basic developmental processes in vitro as well as for drug screening, modeling …