The aim of this study was to efficiently expand less differentiated tenocytes with minimum
use of fetal bovine serum (FBS) for tenocyte‐based tendon tissue engineering. To achieve …

We have established that human tenocytes can differentiate in the absence of exogenous
fetal bovine serum (FBS) but in the presence of insulin-like growth factor-1 (IGF-1) and …

In order to examine the differentiation potential of the tenocytes expanded in our defined
culture medium (reported previously) and the effect of sequential combination of the two …

Tendons are integral to our daily lives by allowing movement and locomotion but are
frequently injured, leading to patient discomfort and impaired mobility. Current clinical …

Abstract Development of regenerative therapies for damaged tendons remains a great
challenge, largely because of lack of information regarding the mechanisms responsible for …

Tendon/ligament injuries are very common in sports and other rigorous activities. Tendons
regenerate and repair slowly and inefficiently in vivo after injury. The limited ability of tendon …

Tendons are associated with a high injury risk because of their overuse and age‐related
tissue degeneration. Thus, tendon injuries pose great clinical and economic challenges to …

Limited supplies of tendon tissue for use in reconstructive surgery require development of
phenotypically stable tenocytes cultivated in vitro. Tenocytes in monolayer culture display an …

Adult tissue stem cells have shown promise for the treatment of debilitating tendon injuries.
However, few comparisons of stem cells from different tissue sources have been made to …

Tenocyte transplantation may prove to be an approach to support healing of tendon defects.
Cell–cell and cell–matrix contacts within three‐dimensional (3D) cultures may prevent …