Plasmids persist in a microbial community by providing fitness benefit to multiple phylotypes

L Li, A Dechesne, JS Madsen, J Nesme… - The ISME …, 2020 - academic.oup.com
The current epidemic of antibiotic resistance has been facilitated by the wide and rapid
horizontal dissemination of antibiotic resistance genes (ARGs) in microbial communities …

Interspecific competition can drive plasmid loss from a focal species in a microbial community

D Sünderhauf, U Klümper, WH Gaze… - The ISME …, 2023 - academic.oup.com
Plasmids are key disseminators of antimicrobial resistance genes and virulence factors, and
it is therefore critical to predict and reduce plasmid spread within microbial communities. The …

Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities

A Alonso-del Valle, R León-Sampedro… - Nature …, 2021 - nature.com
Plasmid persistence in bacterial populations is strongly influenced by the fitness effects
associated with plasmid carriage. However, plasmid fitness effects in wild-type bacterial …

Temperature and Nutrient Limitations Decrease Transfer of Conjugative IncP-1 Plasmid pKJK5 to Wild Escherichia coli Strains

R Pallares-Vega, G Macedo, MSM Brouwer… - Frontiers in …, 2021 - frontiersin.org
Plasmid-mediated dissemination of antibiotic resistance among fecal Enterobacteriaceae in
natural ecosystems may contribute to the persistence of antibiotic resistance genes in …

Plasmid interactions can improve plasmid persistence in bacterial populations

JA Gama, R Zilhão, F Dionisio - Frontiers in Microbiology, 2020 - frontiersin.org
It is difficult to understand plasmid maintenance in the absence of selection and theoretical
models predict the conditions for plasmid persistence to be limited. Plasmid-associated …

Broad host range plasmids can invade an unexpectedly diverse fraction of a soil bacterial community

U Klümper, L Riber, A Dechesne… - The ISME …, 2015 - academic.oup.com
Conjugal plasmids can provide microbes with full complements of new genes and constitute
potent vehicles for horizontal gene transfer. Conjugal plasmid transfer is deemed …

The persistence potential of transferable plasmids

T Wang, L You - Nature communications, 2020 - nature.com
Conjugative plasmids can mediate the spread and maintenance of diverse traits and
functions in microbial communities. This role depends on the plasmid's ability to persist in a …

Timing of antibiotic administration determines the spread of plasmid-encoded antibiotic resistance during microbial range expansion

Y Ma, J Ramoneda, DR Johnson - Nature Communications, 2023 - nature.com
Plasmids are the main vector by which antibiotic resistance is transferred between bacterial
cells within surface-associated communities. In this study, we ask whether there is an …

Fitness costs of plasmids: a limit to plasmid transmission

A San Millan, RC MacLean - Microbiology spectrum, 2017 - Am Soc Microbiol
Plasmids mediate the horizontal transmission of genetic information between bacteria,
facilitating their adaptation to multiple environmental conditions. An especially important …

Emergence of plasmid stability under non-selective conditions maintains antibiotic resistance

T Wein, NF Hülter, I Mizrahi, T Dagan - Nature communications, 2019 - nature.com
Plasmid acquisition is an important mechanism of rapid adaptation and niche expansion in
prokaryotes. Positive selection for plasmid-coded functions is a major driver of plasmid …