Both ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are common, highly heritable
conditions, the pathogenesis of which are incompletely understood. Gene-mapping studies …

The findings suggest that further genome-wide studies in large case–control cohorts are
likely to be very productive in this disease. The IL23R findings and subsequent …

Ankylosing spondylitis (AS) is a common form of inflammatory spinal arthritis with a complex
polygenic aetiology. Genome-wide association studies have identified more than 100 loci …

The advent of high-throughput SNP genotyping methods has advanced research into the
genetics of common complex genetic diseases such as ankylosing spondylitis (AS) rapidly …

Ankylosing spondylitis (AS) is a complex disease involving multiple risk factors, both genetic
and environmental. AS patients are predominantly young men, and the disease is …

There is strong evidence from twin and family studies indicating that a substantial proportion
of the heritability of susceptibility to ankylosing spondylitis (AS) and its clinical manifestations …

Spondyloarthritis refers to a group of inflammatory rheumatic diseases that share common
clinical and genetic characteristics. Due to the rapid advances in technology and …

Ankylosing spondylitis (AS) is the prototypic form of axial spondyloarthritis (axSpA). It is
highly heritable, with studies conducted in twins and in unrelated cases and controls …

Ankylosing spondylitis (AS), an immune-mediated arthritis, is the prototypic member of a
group of conditions known as spondyloarthropathies that also includes reactive arthritis …

Genome-wide association studies (GWAS) have identified 113 single nucleotide
polymorphisms (SNPs) affecting the risk of developing ankylosing spondylitis (AS), and an …