The neurosteroids allopregnanolone and dehydroepiandrosterone modulate resting‐state amygdala connectivity
The neurosteroids allopregnanolone and dehydroepiandrosterone (DHEA) are integral
components of the stress response and exert positive modulatory effects on emotion in both …
components of the stress response and exert positive modulatory effects on emotion in both …
Allopregnanolone elevations following pregnenolone administration are associated with enhanced activation of emotion regulation neurocircuits
BACKGROUND: The neurosteroid allopregnanolone is a potent allosteric modulator of the
gamma-aminobutyric acid type A receptor with anxiolytic properties. Exogenous …
gamma-aminobutyric acid type A receptor with anxiolytic properties. Exogenous …
DHEA enhances emotion regulation neurocircuits and modulates memory for emotional stimuli
Dehydroepiandrosterone (DHEA) is a neurosteroid with anxiolytic, antidepressant, and
antiglucocorticoid properties. It is endogenously released in response to stress, and may …
antiglucocorticoid properties. It is endogenously released in response to stress, and may …
A human chemosignal modulates frontolimbic activity and connectivity in response to emotional stimuli
Evidence suggests the putative human pheromone Δ4, 16-androstadien-3-one
(androstadienone), a natural component of human sweat, increases attention to emotional …
(androstadienone), a natural component of human sweat, increases attention to emotional …
Effects of stress-related neuromodulators on amygdala and hippocampus resting state functional connectivity
Background: The human stress response is characterized by increases in neuromodulators,
including norepinephrine (NE) and cortisol. Both neuromodulators can enter the brain and …
including norepinephrine (NE) and cortisol. Both neuromodulators can enter the brain and …
Corticosteroid induced decoupling of the amygdala in men
MJAG Henckens, GA van Wingen, M Joels… - Cerebral …, 2012 - academic.oup.com
The amygdala is a key regulator of vigilance and heightens attention toward threat. Its
activity is boosted upon threat exposure and contributes to a neuroendocrine stress …
activity is boosted upon threat exposure and contributes to a neuroendocrine stress …
[HTML][HTML] Sex differences in the functional connectivity of the amygdalae in association with cortisol
Human amygdalae are involved in various behavioral functions such as affective and stress
processing. For these behavioral functions, as well as for psychophysiological arousal …
processing. For these behavioral functions, as well as for psychophysiological arousal …
Progesterone selectively increases amygdala reactivity in women
GA Van Wingen, F Van Broekhoven, RJ Verkes… - Molecular …, 2008 - nature.com
The acute neural effects of progesterone are mediated by its neuroactive metabolites
allopregnanolone and pregnanolone. These neurosteroids potentiate the inhibitory actions …
allopregnanolone and pregnanolone. These neurosteroids potentiate the inhibitory actions …
Amygdala subnuclei resting-state functional connectivity sex and estrogen differences
The amygdala is a hub in emotional processing, including that of negative affect. Healthy
men and women have distinct differences in amygdala responses, potentially setting the …
men and women have distinct differences in amygdala responses, potentially setting the …
Amygdala connectivity mediates the association between anxiety and depression in patients with major depressive disorder
C He, L Gong, Y Yin, Y Yuan, H Zhang, L Lv… - Brain imaging and …, 2019 - Springer
Anxiety is the most frequently co-occurring symptom with depression and subsequently
contributes to increased severity and treatment resistance in patients with major depressive …
contributes to increased severity and treatment resistance in patients with major depressive …