Macrophages are mononuclear phagocytes that are widely distributed throughout the body.
These cells can contribute to development and homeostasis and participate in innate and …

Macrophage populations exhibit a wide range of antigenic and functional phenotypes,
including cytokine production, response to immunomodulatory stimuli, and clearance of …

Phagocytes are the founding pillars of innate immunity [1] and, as such, have been the
object of intense scrutiny in the past few years. Mononuclear phagocytes constitute a system …

The last decade has been somewhat of a renaissance period for the field of macrophage
biology. This renewed interest, combined with the advent of new technologies and …

Originally recognized as an essential part of the innate and acquired immune systems,
macrophages emerged as omnipresent and influential regulators of embryo‐and organo …

Classical and non-classical monocytes, and the macrophages and monocyte-derived
dendritic cells they produce, play key roles in host defense against pathogens, immune …

The mononuclear phagocyte system (MPS) is a family of functionally related cells including
bone marrow precursors, blood monocytes, and tissue macrophages. We review the …

Macrophages perform critical functions for homeostasis and immune defense in tissues
throughout the body. These innate immune cells are capable of recognizing and clearing …

Macrophages are unique cells for origin, heterogeneity and plasticity. At steady state most of
macrophages are derived from fetal sources and maintained in adulthood through self …

Macrophages populate every organ during homeostasis and disease, displaying features of
tissue imprinting and heterogeneous activation. The disconnected picture of macrophage …