Cardiovascular effects of erythropoietin: an update

AVR Santhanam, LV d'Uscio, ZS Katusic - Advances in pharmacology, 2010 - Elsevier
Erythropoietin (EPO) is a therapeutic product of recombinant DNA technology and it has
been in clinical use as stimulator of erythropoiesis over the last two decades. Identification of …

Erythropoietin and treatment of non-anemic conditions—cardiovascular protection

D Fliser, H Haller - Seminars in hematology, 2007 - Elsevier
The well-established physiological function of erythropoietin (EPO) is the induction of
erythropoiesis. A growing body of evidence indicates that EPO has tissue-protective effects …

Molecular basis of cardioprotection by erythropoietin

D Burger, A Xenocostas… - Current molecular …, 2009 - ingentaconnect.com
Erythropoietin (EPO), a glycoprotein essential for red blood cell production acts on several
non-erythropoietic tissues. The EPO receptor (EPOR) is expressed in a variety of cell types …

Current perspectives on protective roles of erythropoietin in cardiovascular system: erythropoietin receptor as a novel therapeutic target

Y Kagaya, Y Asaumi, W Wang, M Takeda… - The Tohoku Journal of …, 2012 - jstage.jst.go.jp
Erythropoietin (EPO) is a principal regulator that promotes proliferation and terminal
differentiation of erythroid progenitor cells. EPO receptors are expressed not only in …

Survival and proliferative roles of erythropoietin beyond the erythroid lineage

CT Noguchi, L Wang, HM Rogers, R Teng… - Expert reviews in …, 2008 - cambridge.org
Since the isolation and purification of erythropoietin (EPO) in 1977, the essential role of EPO
for mature red blood cell production has been well established. The cloning of the EPO gene …

Structure, production and function of erythropoietin: implications for therapeutical use in cardiovascular disease

D Mocini, T Leone, M Tubaro… - Current medicinal …, 2007 - ingentaconnect.com
Erythropoietin (EPO) is a 30,400 daltons glycoprotein, consisting of 165 amino acids
produced mainly in the kidney and in the liver and regulating erythrocyitosis. It primarily acts …

An update on the cardiac effects of erythropoietin cardioprotection by erythropoietin and the lessons learnt from studies in neuroprotection

MA Bogoyevitch - Cardiovascular research, 2004 - academic.oup.com
Erythropoietin (Epo) was once thought to act exclusively in the formation of red blood cells.
As recently reviewed by Smith et al.[Cardiovasc. Res. 59 (2003) 538–548], Epo can also act …

[HTML][HTML] Erythropoietin update 2011

M Kowalczyk, M Banach, DP Mikhailidis… - … Medical Journal of …, 2011 - ncbi.nlm.nih.gov
Traditionally, erythropoietin (EPO) is described as a hematopoietic cytokine, regulating
proliferation and differentiation and survival of the erythroid progenitors. The recent finding …

Erythropoietin and the heart: physiological effects and the therapeutic perspective

F Sanchis-Gomar, JL Garcia-Gimenez… - International journal of …, 2014 - Elsevier
Erythropoietin (Epo) has been thought to act exclusively on erythroid progenitor cells. The
identification of Epo receptor (EpoR) in non-haematopoietic cells and tissues including …

Erythropoietin: a new perspective in cardiovascular therapy

R Raddino, D Robba, G Caretta… - … Archives for Chest …, 2008 - monaldi-archives.org
Erythropoietin is a hormone produced by the kidney, which regulates proliferation,
differentiation and maturation of red cells. Recombinant human EPO (rH-EPO) is well known …