Pharmacotherapy of obesity: an update on the available medications and drugs under investigation

M Chakhtoura, R Haber, M Ghezzawi, C Rhayem… - …, 2023 - thelancet.com
Obesity is an epidemic and a public health threat. Medical weight management remains one
of the options for the treatment of excess weight and recent advances have revolutionized …

New medications for treatment of obesity: metabolic and cardiovascular effects

A Pucci, N Finer - Canadian Journal of Cardiology, 2015 - Elsevier
The management of obesity remains a major challenge. Dietary therapy often fails, whereas
bariatric surgery, although successful, is demanding and applicable to a limited number of …

Future pharmacotherapy for obesity: new anti-obesity drugs on the horizon

G Srivastava, C Apovian - Current obesity reports, 2018 - Springer
Abstract Purpose of Review Obesity is a global health crisis with detrimental effects on all
organ systems leading to worsening disease state and rising costs of care. Persons with …

Drug treatment of obesity: current status and future prospects

AK Kakkar, N Dahiya - European Journal of Internal Medicine, 2015 - Elsevier
Obesity is a growing epidemic and a major contributor to the global burden of disease.
Obesity strains the healthcare systems and has profound economic and psychosocial …

Pharmacotherapy in obesity: a systematic review and meta-analysis of randomized controlled trials of anti-obesity drugs

AK Singh, R Singh - Expert review of clinical pharmacology, 2020 - Taylor & Francis
Introduction: Obesity poses a significant increase in morbidity and mortality and thus five anti-
obesity drugs have been approved currently by US FDA. Several phase 3 trials have shown …

[HTML][HTML] Comprehensive review of current and upcoming anti-obesity drugs

JW Son, S Kim - Diabetes & metabolism journal, 2020 - synapse.koreamed.org
Obesity is among the leading causes of morbidity and mortality worldwide and its
prevalence continues to increase globally. Because obesity is a chronic, complex, and …

[HTML][HTML] Pharmacologic therapy of obesity: mechanisms of action and cardiometabolic effects

PD Montan, A Sourlas, J Olivero, D Silverio… - Annals of …, 2019 - ncbi.nlm.nih.gov
Obesity is a chronic, relapsing, multifactorial disease, which has become a serious threat to
public health globally, as the worldwide prevalence of obesity increases exponentially over …

Pharmacotherapy for obesity: novel agents and paradigms

S Manning, A Pucci, N Finer - Therapeutic advances in …, 2014 - journals.sagepub.com
Public health initiatives focused on obesity prevention and lifestyle intervention programmes
for patients with obesity have struggled to contain the obesity epidemic to date. In recent …

Anti-obesity drugs: a critical review of current therapies and future opportunities

JC Clapham, JRS Arch, M Tadayyon - Pharmacology & therapeutics, 2001 - Elsevier
The last 25 years have seen a great increase in the incidence of obesity, both in the Western
world and in developing third world countries. Despite the seeming inexorable progression …

Updates on obesity pharmacotherapy

A Velazquez, CM Apovian - Annals of the New York Academy …, 2018 - Wiley Online Library
Obesity is a chronic, relapsing disease that necessitates a multidisciplinary approach to
management. Behavioral changes are the foundation to management, but adjunctive …