In this review, transition‐metal‐catalyzed intermolecular hydroacylation, which is a direct
synthetic protocol generating ketones from aldehydes and unsaturated hydrocarbons, will …

The catalytic activation and subsequent functionalization of CH bonds is an attractive goal
for synthetic chemists, with reactions that employ low catalyst loadings and result in the …

Activation of the aldehydic carbon-hydrogen bond by transition-metal complexes has
especially received interest because of its relevance to organic synthesis through …

The CH bond of aldehyde can be cleaved by a transition metal complex to give acylmetal
hydride. If subsequent decarbonylation is suppressed, hydroacylation of olefin can proceed …

β-Thioacetal-substituted aldehydes, which are conveniently prepared from the
corresponding ynals, can be combined with a range of alkynes or electron-poor alkenes to …

The hydroacylation of multiple bonds is a highly versatile reaction that uses abundant
starting materials such as alkenes and aldehydes for the formation of valuable ketone …

Prior examples of hydroacylation to form six-and seven-membered ring ketones require
either embedded chelating groups or other substrate design strategies to circumvent …

Intermolecular hydroacylation is one of the most efficient methods for preparing ketones from
olefins and aldehydes.[1] Recently, we developed an efficient catalytic system for the …

This highlight discusses developments in transition metal-catalysed alkene and alkyne
hydroacylation reactions over the past three years. The discussion summarizes the …

General Information. Commercial reagents were purified prior to use following the
guidelines of Perrin and Armarego. 1 Unless otherwise specified, all reactions were …