A dynamic COVID-19 immune signature includes associations with poor prognosis
Improved understanding and management of COVID-19, a potentially life-threatening
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …
[HTML][HTML] Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions
COVID-19 has become a global pandemic. Immune dysregulation has been implicated, but
immune responses remain poorly understood. We analyzed 71 COVID-19 patients …
immune responses remain poorly understood. We analyzed 71 COVID-19 patients …
A consensus Covid-19 immune signature combines immuno-protection with discrete sepsis-like traits associated with poor prognosis
AG Laing, A Lorenc, I Del Molino Del Barrio, A Das… - MedRxiv, 2020 - medrxiv.org
Person-to-person transmission of SARS-CoV-2 virus has triggered a global emergency
because of its potential to cause life-threatening Covid-19 disease. By comparison to …
because of its potential to cause life-threatening Covid-19 disease. By comparison to …
Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19
ER Mann, M Menon, SB Knight, JE Konkel… - Science …, 2020 - science.org
COVID-19 pathogenesis is associated with an exaggerated immune response. However, the
specific cellular mediators and inflammatory components driving diverse clinical disease …
specific cellular mediators and inflammatory components driving diverse clinical disease …
[HTML][HTML] Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia
Immune profiling of COVID-19 patients has identified numerous alterations in both innate
and adaptive immunity. However, whether those changes are specific to SARS-CoV-2 or …
and adaptive immunity. However, whether those changes are specific to SARS-CoV-2 or …
Single-cell landscape of immunological responses in patients with COVID-19
Abstract In coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection, the relationship between disease severity …
syndrome coronavirus 2 (SARS-CoV-2) infection, the relationship between disease severity …
A single-cell atlas of the peripheral immune response in patients with severe COVID-19
There is an urgent need to better understand the pathophysiology of Coronavirus disease
2019 (COVID-19), the global pandemic caused by SARS-CoV-2, which has infected more …
2019 (COVID-19), the global pandemic caused by SARS-CoV-2, which has infected more …
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
INTRODUCTION Many patients with coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, present with …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, present with …
Single-cell multi-omics analysis of the immune response in COVID-19
Abstract Analysis of human blood immune cells provides insights into the coordinated
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses
SARS-CoV-2 causes a spectrum of COVID-19 disease, the immunological basis of which
remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or …
remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or …