Regulated expression of p150, 95 (CD11c/CD18; αX/β2) and VLA‐4 (CD49d/CD29; α4/β1) integrins during myeloid cell differentiation

T Bellóan, C López‐Rodríguez… - European journal of …, 1994 - Wiley Online Library
Integrins are a family of cell surface heterodimers which mediate both cell‐cell and cell‐
extracellular matrix interactions and affect cellular differentiation through their signal …

Identification of Sp1‐binding sites in the CD11c (p150, 95α) and CD11a (LFA‐1α) integrin subunit promoters and their involvement in the tissuespecific expression of …

C López‐Rodríguez, HM Chen… - European journal of …, 1995 - Wiley Online Library
The leukocyte integrins LFA‐1 (CD11a/CD18) and p150, 95 (CD11c/CD18) mediate cell‐
cell and cell‐extracellular matrix interactions during inflammatory responses and signal …

Hematopoietic cell-type-dependent regulation of leukocyte integrin functional activity: CD11b and CD11c expression inhibits LFA-1-dependent aggregation of …

A Nueda, C López-Rodrı́guez, MA Rubio, M Sotillos… - Cellular …, 1995 - Elsevier
To study the influence of the cellular environment on the functional activity of leukocyte
integrins and to analyze their involvement in hematopoietic cell differentiation, we have …

Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering

C Rüegg, AA Postigo, EE Sikorski, EC Butcher… - The Journal of cell …, 1992 - rupress.org
Integrins are heterodimeric cell surface proteins that mediate both cell-cell and cell-
extracellular matrix interactions. We and others recently identified cDNAs encoding a novel …

The leukocyte integrin gene CD11c is transcriptionally regulated during monocyte differentiation

JD Noti, BC Reinemann - Molecular immunology, 1995 - Elsevier
The leukocyte integrins, LFA-1, Mac-1 and p150, 95, are heterodimeric proteins that consist
of a distinct α and a common β subunit. The β subunit gene (CD18) is constitutively …

Cloning and sequence analysis of a novel β2related integrin transcript from T lymphocytes: homology of integrin cysteine-rich repeats to domain III of laminin B chains

Q Yuan, WM Jiang, GW Krissansen… - International …, 1990 - academic.oup.com
The integrins have been grouped into three subfamilies based on the utilization of three
distinct beta chain subunits, β1, β2 and β3. The recent discovery of β4 and β5 subunits, and …

Mapping of the human VLA‐α4 gene to chromosome 2q31‐q32

E Fernández‐Ruiz, FPM de Villena… - European journal of …, 1992 - Wiley Online Library
Abstract The integrin VLA‐4 (α4: β1; CD49d/CD29) is involved in both cellular adhesion to
extracellular matrix and cell‐cell interactions. We have determined that the human gene …

[引用][C] Chromosomal ocations fo the genes coding for the integrin β6 and β7 subunits

GW Krissansen, Q Yuan, D Jenkins, WM Jiang… - Immunogenetics, 1992 - Springer
Integrins are a large family of a/3 subunit receptors, expressed at the cell surface, which
mediate cell-cell and cell-matrix interactions during many biological processes including …

Functions of α4-and β7-integrins in hematopoiesis, lymphocyte trafficking and organ development

N Wagner, W Müller - Leukocyte Integrins in the Immune System and …, 1998 - Springer
The family of integrins comprise more than 20< x~ heterodimeric membrane bound
glycoproteins that mediate cell-cell and cell-extracellular matrix contacts. To date, 16< x and …

[HTML][HTML] Characterization of the CD11a (alpha L, LFA-1 alpha) integrin gene promoter.

A Nueda, M Lopez-Cabrera, A Vara, AL Corbi - Journal of Biological …, 1993 - Elsevier
Human lymphocyte function-associated antigen-1 (LFA-1, CD11a/CD18, alpha L/beta 2) is a
cell surface heterodimer, which, together with Mac-1 (CD11b/CD18, alpha M/beta 2) and …