One key aspect of human aging is the dysregulation of the immune system. As we age, our
body's defense system weakens, leading to declined responses to infection by new …

Aging population is at higher risk of developing severe COVID-19, including hospitalization
and death. In this work, to further understand the relationship between host age-related …

The COVID-19 pandemic drastically highlighted the vulnerability of the elderly population
towards viral and other infectious threats, illustrating that aging is accompanied by …

Age-associated changes in immune cells have been linked to an increased risk for infection.
However, a global and detailed characterization of the changes that human circulating …

Aging is a major risk factor for developing severe COVID-19, but few detailed data are
available concerning immunological changes after infection in aged individuals. Here we …

Background Coronavirus disease 2019 (COVID-19)-induced mortality occurs predominantly
in older patients. Several immunomodulating therapies seem less beneficial in these …

The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

An effective but balanced cellular and inflammatory immune response may limit the severity
of coronavirus disease (COVID-19), whereas uncontrolled inflammation leads to disease …

Aging is an important factor affecting the deterioration of patients with coronavirus disease
2019 (COVID-19). The aging and degeneration of various tissues and organs in the elderly …

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …