A temperature-regulated catalyst-free photoinduced selective carbene C–H insertion
strategy was realized to efficiently synthesize spiro-β-lactones and-lactams, which hold …

Cyclopropane-fused lactones are highly desirable in drug and natural products synthesis.
Herein, we report on a photochemical, chemoselective reaction of aryldiazoacetates with …

Visible-light-mediated sequential Wolff rearrangement and Staudinger cycloaddition for the
assembly of valuable spiro-pyrazolone-β-lactams for the first time is disclosed by utilizing in …

The development of green and sustainable approaches for the synthesis of small molecules
is always in demand. Oxetanes and azetidines are strained heterocycles that possess …

Carboxylic esters are an excellent choice of substrates in organic synthesis. Here we
demonstrate that carbene-catalyzed activation of α, β-unsaturated ester can be developed to …

Heterocyclic skeletons are commonly found in various bioactive molecules and
pharmaceutical compounds, making them crucial in areas such as medicinal chemistry …

Herein, we report a blue visible-light-promoted approach for preparing a variety of α-
substituted γ-ketoester derivatives through carbene insertion and the decarbonylation of …

This work develops a photocatalysis method for the synthesis of γ-spirolactams through a
tandem intramolecular 1, 5-HAT reaction–cyclization process. A variety of novel γ …

A visible-light-mediated strategy is reported for the efficient synthesis of multisubstituted
pyrazoles through a three-component carbene transfer reaction of α-diazoesters with cyclic …

While N-alkenoxypyridinium salts are widely used for the synthesis of α-functionalized
ketones via umpolung strategy, such approaches are usually limited to special nucleophiles …