Janus kinase/signal transduction and transcription activation (JAK/STAT) pathways were
originally thought to be intracellular signaling pathways that mediate cytokine signals in …

The JAK/STAT signaling pathway is an universally expressed intracellular signal
transduction pathway and involved in many crucial biological processes, including cell …

The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling
pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular …

The Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway
plays critical roles in orchestrating of immune system, especially cytokine receptors and they …

The cytokine-activated Janus kinase (JAK)–signal transducer and activator of transcription
(STAT) pathway has an important role in the control of immune responses. Dysregulation of …

The Janus kinase (JAK) signal transducer and activator of transcription (JAK-STAT) pathway
is an evolutionarily conserved mechanism of transmembrane signal transduction that …

The Janus kinase-signal transducer and activator of transcription (Jak-STAT) pathway is
essential for the signal transduction of many cytokines. Dysregulation of Jak-STAT signaling …

Background: JAK/STAT signal pathway, a requisite part in the signaling process of growth
factors and cytokines, has become attractive targets for numerous immune, inflammatory …

Cytokines are molecules that play critical roles in the regulation of a wide range of normal
functions leading to cellular proliferation, differentiation and survival, as well as in …

Antibodies that block cytokine function provide a powerful therapeutic tool especially for the
treatment of autoimmune diseases. Cytokines are a group of small hydrophilic glycoproteins …