Cross-neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike
Several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have
arisen that exhibit increased viral transmissibility and partial evasion of immunity induced by …
arisen that exhibit increased viral transmissibility and partial evasion of immunity induced by …
A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants
J Zhang, ZB Han, Y Liang, XF Zhang, YQ Jin, LF Du… - Elife, 2022 - elifesciences.org
Large-scale populations in the world have been vaccinated with COVID-19 vaccines,
however, breakthrough infections of SARS-CoV-2 are still growing rapidly due to the …
however, breakthrough infections of SARS-CoV-2 are still growing rapidly due to the …
Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice
T Noy-Porat, A Mechaly, Y Levy, E Makdasi, R Alcalay… - Iscience, 2021 - cell.com
Neutralizing antibodies represent a valuable therapeutic approach to countermeasure the
current COVID-19 pandemic. Emergence of SARS-CoV-2 variants emphasizes the notion …
current COVID-19 pandemic. Emergence of SARS-CoV-2 variants emphasizes the notion …
Current status and perspectives of therapeutic antibodies targeting the spike protein S2 subunit against SARS-CoV-2
Y Yamamoto, T Inoue - Biological and Pharmaceutical Bulletin, 2024 - jstage.jst.go.jp
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has devastated public health and the …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has devastated public health and the …
Structures of potent and convergent neutralizing antibodies bound to the SARS-CoV-2 spike unveil a unique epitope responsible for exceptional potency
S Du, Y Cao, Q Zhu, G Wang, X Du, R He, H Xu… - BioRxiv, 2020 - biorxiv.org
Understanding the mechanism of neutralizing antibodies (NAbs) against SARS-CoV-2 is
critical for effective vaccines and therapeutics development. We recently reported an …
critical for effective vaccines and therapeutics development. We recently reported an …
A broadly neutralizing antibody inhibits SARS-CoV-2 variants through a novel mechanism of disrupting spike trimer integrity
Y Ma, Q Mao, Y Wang, Z Zhang, J Chen, A Hao… - Cell Research, 2023 - nature.com
Dear Editor, Since the start of the COVID-19 pandemic, thousands of neutralizing antibodies
(NAbs) targeting different epitopes of the spike protein have been identified and …
(NAbs) targeting different epitopes of the spike protein have been identified and …
SARS-CoV-2 spike S2-specific neutralizing antibodies
CJ Li, SC Chang - Emerging Microbes & Infections, 2023 - Taylor & Francis
Since the onset of the coronavirus disease 2019 (COVID-19), numerous neutralizing
antibodies (NAbs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
antibodies (NAbs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
An elite broadly neutralizing antibody protects SARS-CoV-2 Omicron variant challenge
The strikingly high transmissibility and antibody evasion of SARS-CoV-2 Omicron variant
have posted great challenges on the efficacy of current vaccines and antibody …
have posted great challenges on the efficacy of current vaccines and antibody …
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD
H Sun, T Deng, Y Zhang, Y Lin, Y Jiang, Y Jiang… - Protein & …, 2024 - academic.oup.com
Continual evolution of the severe acute respiratory syndrome coronavirus (SARS-CoV-2)
virus has allowed for its gradual evasion of neutralizing antibodies (nAbs) produced in …
virus has allowed for its gradual evasion of neutralizing antibodies (nAbs) produced in …
Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209
Dear Editor, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and its variants is still a pandemic raging across the …
syndrome coronavirus 2 (SARS-CoV-2) and its variants is still a pandemic raging across the …