Continuous base identification for single-molecule nanopore DNA sequencing
A single-molecule method for sequencing DNA that does not require fluorescent labelling
could reduce costs and increase sequencing speeds. An exonuclease enzyme might be …
could reduce costs and increase sequencing speeds. An exonuclease enzyme might be …
Highly parallel direct RNA sequencing on an array of nanopores
Sequencing the RNA in a biological sample can unlock a wealth of information, including
the identity of bacteria and viruses, the nuances of alternative splicing or the transcriptional …
the identity of bacteria and viruses, the nuances of alternative splicing or the transcriptional …
Recent trends in nanopores for biotechnology
DH Stoloff, M Wanunu - Current opinion in biotechnology, 2013 - Elsevier
Nanopore technology employs a nanoscale hole in an insulating membrane to
stochastically sense with high throughput individual biomolecules in solution. The generality …
stochastically sense with high throughput individual biomolecules in solution. The generality …
Oxford Nanopore announcement sets sequencing sector abuzz
O Nanopore - Nat. Biotechnol, 2012 - nature.com
© 2012 Nature America, Inc. All rights reserved. 296 volume 30 number 4 APrIl 2012
NATURE BIoTECHNoloGy volume, nobody in their right mind would invest in a short …
NATURE BIoTECHNoloGy volume, nobody in their right mind would invest in a short …
Improved data analysis for the MinION nanopore sequencer
Speed, single-base sensitivity and long read lengths make nanopores a promising
technology for high-throughput sequencing. We evaluated and optimized the performance of …
technology for high-throughput sequencing. We evaluated and optimized the performance of …
[HTML][HTML] DNA assembly for nanopore data storage readout
Synthetic DNA is becoming an attractive substrate for digital data storage due to its density,
durability, and relevance in biological research. A major challenge in making DNA data …
durability, and relevance in biological research. A major challenge in making DNA data …
ReadBouncer: precise and scalable adaptive sampling for nanopore sequencing
Motivation Nanopore sequencers allow targeted sequencing of interesting nucleotide
sequences by rejecting other sequences from individual pores. This feature facilitates the …
sequences by rejecting other sequences from individual pores. This feature facilitates the …
[HTML][HTML] Fast nanopore sequencing data analysis with SLOW5
H Gamaarachchi, H Samarakoon, SP Jenner… - Nature …, 2022 - nature.com
Nanopore sequencing depends on the FAST5 file format, which does not allow efficient
parallel analysis. Here we introduce SLOW5, an alternative format engineered for efficient …
parallel analysis. Here we introduce SLOW5, an alternative format engineered for efficient …
BulkVis: a graphical viewer for Oxford nanopore bulk FAST5 files
Abstract Motivation The Oxford Nanopore Technologies (ONT) MinION is used for
sequencing a wide variety of sample types with diverse methods of sample extraction …
sequencing a wide variety of sample types with diverse methods of sample extraction …
[HTML][HTML] Assessing the performance of the oxford nanopore technologies minion
T Laver, J Harrison, PA O'neill, K Moore… - Biomolecular detection …, 2015 - Elsevier
Abstract The Oxford Nanopore Technologies (ONT) MinION is a new sequencing technology
that potentially offers read lengths of tens of kilobases (kb) limited only by the length of DNA …
that potentially offers read lengths of tens of kilobases (kb) limited only by the length of DNA …