Carboplatin (Paraplatin; JM8) and etoposide (VP-16) as first-line combination therapy for small-cell lung cancer.

IE Smith, BD Evans, ME Gore, MD Vincent… - Journal of Clinical …, 1987 - ascopubs.org
Fifty-two previously untreated patients with small-cell lung carcinoma (SCLC) were treated
with a combination of carboplatin 300 mg/m2 intravenously (IV) on day 1 and etoposide 100 …

Etoposide and split-dose cisplatin in small-cell lung cancer

H Wilke, W Achterrath, HJ Schmoll… - American journal of …, 1988 - journals.lww.com
Forty-seven untreated patients with small-cell lung cancer (SCLC) were treated with a
combination of etoposide (170 mg/m 2 intravenously, iv, days 3–5) and cisplatin (50 mg/m 2 …

Carboplatin, etoposide, and ifosfamide as intensive chemotherapy for small-cell lung cancer.

IE Smith, TJ Perren, SA Ashley, J Woodiwiss… - Journal of Clinical …, 1990 - ascopubs.org
Thirty-two previously untreated, fit patients with small-cell lung carcinoma (SCLC) were
treated with an intensive combination chemotherapy regimen, with the aim of prolonging …

Carboplatin (CBDCA, JM-8) and VP-16-213 in previously untreated patients with small-cell lung cancer.

JF Bishop, D Raghavan, R Stuart-Harris… - Journal of Clinical …, 1987 - ascopubs.org
The efficacy and toxicity of carboplatin 100 mg/m2, administered intravenously (IV) daily X 3,
and VP-16-213 120 mg/m2, IV daily X 3, administered every 28 days for six courses, was …

Cisplatin and etoposide (VP‐16) as a single regimen for small cell lung cancer. A phase II trial

C Boni, G Cocconi, G Bisagni, G Ceci, G Peracchia - Cancer, 1989 - Wiley Online Library
Forty‐seven consecutive patients with small cell lung cancer (SCLC) were treated with a
combination chemotherapy program including 60 mg/m2 of cisplatin (P) on day 1 and 120 …

Phase II study of carboplatin in previously untreated patients with metastatic small cell lung carcinoma.

RH Jacobs, JD Bitran, M Deutsch… - Cancer treatment …, 1987 - europepmc.org
Fourteen previously untreated patients with metastatic small cell lung carcinoma (SCLC)
were treated with carboplatin, 400 mg/m2, given as a 1-hour infusion every 28 days. Eleven …

Doxorubicin, cyclophosphamide, etoposide and platinum, doxorubicin, cyclophosphamide and etoposide for small-cell carcinoma of the lung.

J Aisner, M Whitacre, J Abrams, K Propert - Seminars in oncology, 1986 - europepmc.org
Small-cell lung cancer (SCLC) is a disseminated disease regardless of our ability to
document all sites. Chemotherapy is thus the cornerstone of treatment. There are multiple …

The role of carboplatin in the treatment of small-cell lung cancer.

DS Ettinger - Oncology (Williston Park, NY), 1998 - europepmc.org
Lung cancer is the leading cause of death due to cancer in the United States, and
approximately 178,100 new cases were estimated to occur last year. Small-cell lung cancer …

Cisplatin, doxorubicin, cyclophosphamide, and etoposide combination chemotherapy for small-cell lung cancer

J Aisner, MY Whitacre, DR Budman, K Propert… - Cancer chemotherapy …, 1992 - Springer
Because of potential synergistic interactions, we added 25 mg/m 2 iv cisplatin (P) 25 given
on days 1–5 to the combination of 45 mg/m 2 iv doxorubicin (A) given on day 1, 800 mg/m 2 …

Carboplatin (JM8) as a single agent and in combination in the treatment of small cell lung cancer

IE Smith, BD Evans - Cancer Treatment Reviews, 1985 - Elsevier
Carboplatin, a cisplatin analogue without significant nephrotoxicity, was used as a single
agent in the treatment of 56 patients with small cell lung carcinoma at a dose of 300–400 …