Stem cells in various mammalian organs retain the capacity to renew themselves and may
be able to restore damaged tissue. Their existence has been proven by genetic tracer …

Stem cells in the nervous system have some capacity to restore damaged tissue.
Proliferation of stem cells endows them with self-renewal ability and accounts for in vitro …

The mammalian inner ear has very limited ability to regenerate lost sensory hair cells. This
deficiency becomes apparent when hair cell loss leads to hearing loss as a result of either …

Loss of inner ear hair cells leads to incurable balance and hearing disorders because these
sensory cells do not effectively regenerate in humans. A potential starting point for therapy …

The adult mammalian cochlea lacks regenerative capacity, which is the main reason for the
permanence of hearing loss. Vestibular organs, in contrast, replace a small number of lost …

The mammalian inner ear is vulnerable to genetic disorders and aging, as well as to injuries
caused by overstimulation, ototoxic drugs, and viral infections. Due to the poor regeneration …

In light of the currently defined characteristics of stem cells, a re-evaluation of hair cell
regeneration in birds suggests that there may be a stem cell population located in the inner …

Potential treatment strategies of neurodegenerative and other diseases with stem cells
derived from nonembryonic tissues are much less subjected to ethical criticism than …

In vertebrates, perception of sound, motion, and balance is mediated through
mechanosensory hair cells located within the inner ear. In mammals, hair cells are only …

Mammalian cochlear sensory epithelial cells are believed to possess minimal regenerative
potential because they halt proliferation during late stage of embryogenesis and never …